2001
CD8 Binding to MHC Class I Molecules Is Influenced by T Cell Maturation and Glycosylation
Daniels M, Devine L, Miller J, Moser J, Lukacher A, Altman J, Kavathas P, Hogquist K, Jameson S. CD8 Binding to MHC Class I Molecules Is Influenced by T Cell Maturation and Glycosylation. Immunity 2001, 15: 1051-1061. PMID: 11754824, DOI: 10.1016/s1074-7613(01)00252-7.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsATP Binding Cassette Transporter, Subfamily B, Member 2ATP-Binding Cassette TransportersCD3 ComplexCD4-Positive T-LymphocytesCD8 AntigensCD8-Positive T-LymphocytesCell AdhesionCell DifferentiationCellular SenescenceGlycosylationH-2 AntigensHistocompatibility Antigen H-2DLigandsMacromolecular SubstancesMembrane GlycoproteinsMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutN-Acetylneuraminic AcidNeuraminidaseOvalbuminPeptide FragmentsProtein BindingProtein Processing, Post-TranslationalReceptors, Antigen, T-Cell, alpha-betaRheologySolubilityThymus GlandT-Lymphocyte SubsetsConceptsGlycosylation stateT cell maturationCell maturationT cell adhesionDevelopmental regulationDouble-positive thymocytesCell adhesionT cell activationClass I MHC tetramersAdhesion moleculesCell activationMHC class I moleculesMaturationClass I moleculesClass I MHC moleculesI MHC moleculesI moleculesMoleculesGlycosylationMHC ligandsRegulationMHC moleculesClass I MHCBindingSialylation
1996
SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics
Greenwood J, Pryce G, Devine L, Male D, dos Santos W, Calder V, Adamson P. SV40 large T immortalised cell lines of the rat blood-brain and blood-retinal barriers retain their phenotypic and immunological characteristics. Journal Of Neuroimmunology 1996, 71: 51-63. PMID: 8982103, DOI: 10.1016/s0165-5728(96)00130-0.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Polyomavirus TransformingAntigens, SurfaceBiological TransportBlood-Brain BarrierCell Adhesion MoleculesCell MovementCell Transformation, ViralEndotheliumEndothelium, VascularFluorescent Antibody Technique, IndirectHistocompatibility AntigensLipoproteins, LDLPigment Epithelium of EyeRatsRetinaSimian virus 40T-LymphocytesConceptsRetinal pigment epitheliumBlood-retinal barrierRetinal endotheliumAdhesion moleculesCell adhesion moleculeCell linesAntigen-specific T cell linesImmortalised cell linesMajor histocompatibility complex class 1Vascular cell adhesion moleculeRat brain endotheliumMHC class IIEndothelial cell adhesion moleculesIntercellular adhesion moleculeCentral nervous systemLectin Griffonia simplicifoliaPlatelet endothelial cell adhesion moleculeHigh-affinity uptakeT cell linesPigmented epithelial cellsRPE cell lineVon Willebrand factorEndothelial cell lineNeural parenchymaBrain endotheliumRole of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro
DEVINE L, LIGHTMAN S, GREENWOOD J. Role of LFA‐1, ICAM‐1, VLA‐4 and VCAM‐1 in lymphocyte migration across retinal pigment epithelial monolayers in vitro. Immunology 1996, 88: 456-462. PMID: 8774365, PMCID: PMC1456340, DOI: 10.1046/j.1365-2567.1996.d01-666.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlood-Retinal BarrierCD4-Positive T-LymphocytesCell Adhesion MoleculesCell Culture TechniquesCell MovementChemotaxis, LeukocyteEnzyme-Linked Immunosorbent AssayFlow CytometryIntercellular Adhesion Molecule-1Microscopy, ElectronPigment Epithelium of EyeRatsRats, Inbred StrainsVascular Cell Adhesion Molecule-1ConceptsBlood-retinal barrierRetinal pigment epitheliumLFA-1 betaICAM-1VCAM-1VLA-4Vascular endotheliumLymphocyte migrationAntigen-specific T cell linesAdhesion moleculesRetinal vascular endotheliumMigration of CD4Traffic of lymphocytesOcular inflammatory conditionsLFA-1 alphaVCAM-1 expressionRetinal pigment epithelial monolayerRPE cell monolayersT cell linesPosterior uveitisLymphocyte trafficInflammatory conditionsPosterior barrierCell adhesion moleculeIFN-gammaA Comparison of Lymphocyte Migration Across the Anterior and Posterior Blood-Retinal Barrier in Vitro
Devine L, Lightman S, Greenwood J. A Comparison of Lymphocyte Migration Across the Anterior and Posterior Blood-Retinal Barrier in Vitro. Advances In Behavioral Biology 1996, 46: 245-251. DOI: 10.1007/978-1-4757-9489-2_41.Peer-Reviewed Original ResearchBlood-retinal barrierCentral nervous systemRetinal pigment epitheliumImmune mediated diseasesSystemic immune systemVLA-4/VCAMTraffic of lymphocytesLFA-1/ICAMBlood-tissue barriersMediated diseasesCytokine activationLymphocyte migrationVascular endotheliumPigment epitheliumNervous systemImmune systemRPE monolayerAdhesion moleculesLymphocytesVascular endothelialReceptor-ligand pairingsCellular barriersEyesSeparate sitesVCAM