2004
Epidermal desquamation
Milstone LM. Epidermal desquamation. Journal Of Dermatological Science 2004, 36: 131-140. PMID: 15541634, DOI: 10.1016/j.jdermsci.2004.05.004.Commentaries, Editorials and Letters
1999
Growth and differentiation regulate CD44 expression on human keratinocytes
Zhou J, Haggerty J, Milstone L. Growth and differentiation regulate CD44 expression on human keratinocytes. In Vitro Cellular & Developmental Biology - Animal 1999, 35: 228-235. PMID: 10478803, DOI: 10.1007/s11626-999-0031-7.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCell DivisionCells, CulturedEpidermal CellsEpidermisHumansHyaluronan ReceptorsKeratinocytesProteoglycansConceptsCD44 expressionBasal keratinocytesChondroitin sulfate proteoglycan formKeratan sulfate proteoglycanConfluent culturesPreconfluent monolayersDifferentiated cellsHyaluronan receptorWestern immunoblotCD44 proteinHuman keratinocytesCD44 familyKeratinocytesPreconfluent culturesSulfate proteoglycanDifferentiated keratinocytesCD44Core proteinSplice variants
1995
Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis
Schwartz P, Barnett S, Milstone L. Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis. Journal Of Dermatological Science 1995, 9: 129-135. PMID: 7772575, DOI: 10.1016/0923-1811(94)00370-t.Peer-Reviewed Original Research
1992
Methotrexate induces differentiation of human keratinocytes.
Schwartz P, Barnett S, Atillasoy E, Milstone L. Methotrexate induces differentiation of human keratinocytes. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 594-598. PMID: 1731329, PMCID: PMC48285, DOI: 10.1073/pnas.89.2.594.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCell DivisionCells, CulturedHumansIn Vitro TechniquesKeratinocytesMethotrexateProtein PrecursorsProteinsThymidineConceptsEffect of methotrexateAbility of methotrexateProliferation of keratinocytesProportion of cellsMarkers of differentiationHuman epidermal keratinocytesMethotrexateTherapeutic actionEpidermal keratinocytesMarked increaseHuman keratinocytesKeratinocytesEnvelope proteinSDS/PAGE profilesInvolucrin synthesisNormal cellsTerminal differentiationTissue homeostasisThymine deoxyribonucleotidesDifferentiationCellsPsoriasisCell morphologyReproducible changesDose
1991
Quantitation of cross-linked protein: An alternative to counting cornified envelopes as an index of keratinocyte differentiation
Hough-Monroe L, Milstone L. Quantitation of cross-linked protein: An alternative to counting cornified envelopes as an index of keratinocyte differentiation. Analytical Biochemistry 1991, 199: 25-28. PMID: 1807158, DOI: 10.1016/0003-2697(91)90264-t.Peer-Reviewed Original Research
1988
Effector Functions of Epidermal Keratinocytes
MILSTONE L. Effector Functions of Epidermal Keratinocytes. Annals Of The New York Academy Of Sciences 1988, 548: 1-3. PMID: 2470284, DOI: 10.1111/j.1749-6632.1988.tb18787.x.Chapters
1983
GABA from putrescine is bound in macromolecular form in keratinocytes
Canellakis Z, Milstone L, Marsh L, Young P, Bondy P. GABA from putrescine is bound in macromolecular form in keratinocytes. Life Sciences 1983, 33: 599-603. PMID: 6192309, DOI: 10.1016/0024-3205(83)90247-3.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCells, CulturedGamma-Aminobutyric AcidHumansHydrocortisoneKeratinsKineticsMalePutrescineSkinTritiumConceptsGamma-aminobutyric acidAcid-precipitable materialNeurotransmitter gamma-aminobutyric acidTotal cell-associated radioactivityTCA-precipitable radioactivityTCA-soluble radioactivityCultured human keratinocytesTCA-soluble fractionCell-associated radioactivityHuman foreskin keratinocytesTCA-precipitable materialAcid-soluble radioactivityRadioactive metabolitesSoluble radioactivityForeskin keratinocytesStratified culturesHuman keratinocytesKeratinocytesTrichloroacetic acidMacromolecular formRadioactivityPopulation Dynamics in Cultures of Stratified Squamous Epithelia
Milstone L. Population Dynamics in Cultures of Stratified Squamous Epithelia. Journal Of Investigative Dermatology 1983, 81: s69-s74. PMID: 6863993, DOI: 10.1111/1523-1747.ep12540629.Peer-Reviewed Original Research
1976
δ-Crystallin mRNA in chick lens cells: mRNA accumulates during differential stimulation of δ-crystallin synthesis in cultured cells
Milstone L, Zelenka P, Piatigorsky J. δ-Crystallin mRNA in chick lens cells: mRNA accumulates during differential stimulation of δ-crystallin synthesis in cultured cells. Developmental Biology 1976, 48: 197-204. PMID: 1254080, DOI: 10.1016/0012-1606(76)90084-1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCells, CulturedChick EmbryoCrystallinsDNALens, CrystallineRNA, MessengerConceptsΔ-crystallin synthesisChick lens epithelial cellsChick lens cellsEmbryonic lens epitheliumLens fiber cellsLens epithelial cellsFiber cellsLens cellsDifferential stimulationProtein synthesisCultured cellsMRNALens epitheliumEpithelial cellsTissue cultureCellsDifferentiationOverall stimulationAccumulationStimulationSpecializationCultureSynthesisOvo
1975
Rates of protein synthesis in explanted embryonic chick lens epithelia: Differential stimulation of δ-crystallin synthesis
Milstone L, Piatigorsky J. Rates of protein synthesis in explanted embryonic chick lens epithelia: Differential stimulation of δ-crystallin synthesis. Developmental Biology 1975, 43: 91-100. PMID: 1149925, DOI: 10.1016/0012-1606(75)90133-5.Peer-Reviewed Original ResearchConceptsChick lens epitheliumΔ-crystallin synthesisProtein synthesisΔ-crystallinDifferential protein synthesisLens fiber cellsLens fiber differentiationLens epitheliumProtein degradationFiber cellsFiber differentiationBulk proteinTotal protein synthesisRate of synthesisIntracellular valineLabeling periodNumber of cellsProteinFetal calf serumCellsDifferential stimulationBiochemical changesCalf serumTotal proteinEpithelium
1973
Differentiation of lens fibers in explanted embryonic chick lens epithelia
Piatigorsky J, Rothschild S, Milstone L. Differentiation of lens fibers in explanted embryonic chick lens epithelia. Developmental Biology 1973, 34: 334-345. PMID: 4596973, DOI: 10.1016/0012-1606(73)90362-x.Peer-Reviewed Original ResearchConceptsChick lens epitheliumLens epitheliumLens fibersLens epithelial cellsRibosomal clustersRibosomal RNADelta-crystallinTissue cultureSingle-strand breaksFiber differentiationCell membraneLong cellsMean cell lengthCell lengthTotal RNACellular outgrowthDifferentiationEpithelial cellsSurface membraneRNAOrganelle densityChick embryosGranular matrixBiochemical changesCells