2011
Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features
Ko CJ, Milstone LM, Choi J, McNiff JM. Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features. International Journal Of Dermatology 2011, 50: 1480-1485. PMID: 22097993, DOI: 10.1111/j.1365-4632.2011.04990.x.Peer-Reviewed Original ResearchConceptsCases of PRPPityriasis rubra pilarisCases of erythrodermaCases of psoriasisHistologic featuresClinical contextCorrect clinical settingPresence of acantholysisHailey-Hailey diseaseLichenoid infiltratePapulosquamous lesionsPemphigus vulgarisFocal acantholysisHistologic cluesErythrodermaDarier's diseaseAcantholysisClinical settingDermatology literatureDiseasePsoriasisBiopsyDifferent causesDiagnosisInfiltrates
2008
Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
Leachman SA, Hickerson RP, Hull PR, Smith FJ, Milstone LM, Lane EB, Bale SJ, Roop DR, McLean WH, Kaspar RL. Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita. Journal Of Dermatological Science 2008, 51: 151-157. PMID: 18495438, PMCID: PMC2587483, DOI: 10.1016/j.jdermsci.2008.04.003.Peer-Reviewed Original ResearchConceptsPachyonychia congenitaQuantitative RT-PCRRT-PCRReal-time RT-PCRQuantitative real-time RT-PCRClinical efficacyGenetic skin disordersClinical trialsCandidate siRNASkin disordersRNA interferenceNovel therapeuticsPotent inhibitionTherapeutic siRNAsClinical applicationDisordersGenetic disordersPhysiciansCongenitaMutant allelesSiRNAHuman diseasesKeratin disordersPatientsDisease
2005
Treatment of Pachyonychia Congenita
Milstone LM, Fleckman P, Leachman SA, Leigh IM, Paller AS, van Steensel MA, Swartling C. Treatment of Pachyonychia Congenita. Journal Of Investigative Dermatology Symposium Proceedings 2005, 10: 18-20. PMID: 16250205, DOI: 10.1111/j.1087-0024.2005.10203.x.Peer-Reviewed Original Research
1995
Generalized Linear Porokeratosis Treated With Etretinate
Goldman G, Milstone L. Generalized Linear Porokeratosis Treated With Etretinate. JAMA Dermatology 1995, 131: 496-497. DOI: 10.1001/archderm.1995.01690160126029.Peer-Reviewed Case Reports and Technical NotesConceptsLinear porokeratosisLesions of porokeratosisSquamous cell carcinomaTopical vitamin AYears of ageBowen's diseaseHistologic confirmationTherapeutic challengeVerrucous plaquesCell carcinomaVerrucous lesionsTreatment recommendationsD ointmentVitamin AOnly treatmentPorokeratosisLesionsAnterior partWhite menExtensive casesDiseaseBirthRecreational activitiesEtretinateCarcinoma
1993
Secondary Hyperparathyroidism in Patients With Ichthyosis Is Not Caused by Vitamin D Deficiency or Ingestion of Retinoids
Milstone L, Bale S, Insogna K. Secondary Hyperparathyroidism in Patients With Ichthyosis Is Not Caused by Vitamin D Deficiency or Ingestion of Retinoids. JAMA Dermatology 1993, 129: 648-648. PMID: 8481031, DOI: 10.1001/archderm.1993.01680260120024.Peer-Reviewed Original ResearchConceptsSecondary hyperparathyroidismParathyroid hormoneVitamin DSerum PTH valuesVitamin D deficiencyDisorders of keratinizationNonbullous ichthyosiform erythrodermaD deficiencyPTH levelsPTH valuesClinical findingsBiopsy specimensPatientsDarier's diseaseIchthyosis vulgarisIchthyosiform erythrodermaPlasma samplesLamellar ichthyosisHyperparathyroidismEpidermolytic hyperkeratosisSeparate groupsDiseaseIchthyosisInheritance patternNew Haven
1990
Measurement of retinoid effects on epidermal renewal
Milstone L. Measurement of retinoid effects on epidermal renewal. Methods In Enzymology 1990, 190: 76-81. PMID: 2087197, DOI: 10.1016/0076-6879(90)90011-o.Chapters
1983
Classification and Therapy of Atrophie Blanche
Milstone L, Braverman I, Lucky P, Fleckman P. Classification and Therapy of Atrophie Blanche. JAMA Dermatology 1983, 119: 963-969. PMID: 6651312, DOI: 10.1001/archderm.1983.01650360009005.Peer-Reviewed Original ResearchConceptsAtrophie blancheCommon pathologic eventEndogenous fibrinolytic activityCharacteristic histopathologic featuresPlatelet thrombus formationOcclusion of vesselsMost patientsClinical evolutionHistopathologic featuresPurpuric papulesClinicopathologic entityLower extremitiesPathologic eventsDeep dermisThrombus formationFibrinolytic activityMultiple causesTherapyTreatmentCauseUlcerationPatientsPapulesPathogenesisDisease