Hyperosmotic media inhibit voltage-dependent calcium influx and peptide release in Aplysia neurons
Loechner K, Knox R, Connor J, Kaczmarek L. Hyperosmotic media inhibit voltage-dependent calcium influx and peptide release in Aplysia neurons. The Journal Of Membrane Biology 1992, 128: 41-52. PMID: 1323684, DOI: 10.1007/bf00231869.Peer-Reviewed Original ResearchConceptsBag cell neuronsCell neuronsAction potentialsVoltage-dependent calcium influxVoltage-dependent calcium currentsPotassium-induced depolarizationIntracellular calcium levelsCalcium indicator dyeEffect of hyperosmolalityHyperosmotic mediumCalcium currentCalcium influxFura-2Calcium levelsPeptide secretionCalcium entryAfterdischargesBrief stimulationNeuroactive peptidesNeuronsSecretory propertiesAplysia neuronsHigh potassiumPeptide releaseRelease of peptides