1994
Autoactive peptides act at three distinct receptors to depolarize the bag cell neurons of Aplysia
Loechner K, Kaczmarek L. Autoactive peptides act at three distinct receptors to depolarize the bag cell neurons of Aplysia. Journal Of Neurophysiology 1994, 71: 195-203. PMID: 8158229, DOI: 10.1152/jn.1994.71.1.195.Peer-Reviewed Original Research
1989
THE ROLE OF PROTEIN KINASE C AND PHOSPHOINOSITIDE METABOLITES IN NEURONS THAT CONTROL PROLONGED REPRODUCTIVE BEHAVIORS IN APLYSIA
Kaczmarek L. THE ROLE OF PROTEIN KINASE C AND PHOSPHOINOSITIDE METABOLITES IN NEURONS THAT CONTROL PROLONGED REPRODUCTIVE BEHAVIORS IN APLYSIA. 1989, 129-141. DOI: 10.1016/b978-0-12-375655-8.50014-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1985
Inhibitors of calcium-dependent enzymes prevent the onset of afterdischarge in the peptidergic bag cell neurons of Aplysia
DeRiemer S, Schweitzer B, Kaczmarek L. Inhibitors of calcium-dependent enzymes prevent the onset of afterdischarge in the peptidergic bag cell neurons of Aplysia. Brain Research 1985, 340: 175-180. PMID: 4027644, DOI: 10.1016/0006-8993(85)90790-5.Peer-Reviewed Original ResearchConceptsBag cell neuronsCalcium-dependent enzymesCell neuronsNeuroactive peptidesAttenuation of secretionOnset of afterdischargeBrief electrical stimulationPeptidergic bag cell neuronsAbility of stimulationEffect of TFPEffects of agentsNeuronal excitabilitySynaptic transmissionAfterdischargesNeurosecretory neuronsElectrical stimulationEndogenous burstingNeuronsSecretionCalmodulin-dependent enzymesProtein kinaseAplysiaStimulationOnsetAgentsEnhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C
DeRiemer SA, Strong JA, Albert KA, Greengard P, Kaczmarek LK. Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C. Nature 1985, 313: 313-316. PMID: 2578617, DOI: 10.1038/313313a0.Peer-Reviewed Original ResearchConceptsProtein kinase CKinase CProtein kinase presentEndogenous protein kinase CKinase presentProtein kinase1Molecular mechanismsCellular componentsPhorbol ester TPAIon channelsPhorbol esterMammalian brainTumor-promoting phorbol ester TPAMollusc AplysiaPhysiological propertiesEnzymeNeuronal excitabilityDirect evidenceKinase1PhosphorylationProteinHigh concentrationsActivationAplysia
1982
Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia.
Strumwasser F, Kaczmarek L, Jennings K. Intracellular modulation of membrane channels by cyclic AMP-mediated protein phosphorylation in peptidergic neurons of Aplysia. The FASEB Journal 1982, 41: 2933-9. PMID: 6292000.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProtein phosphorylationCyclic AMPPotassium channelsBag cell neuronsEgg-laying hormoneMembrane channelsIntracellular modulationPhosphorylationPeptidergic bag cell neuronsCell neuronsExact identityPeptidergic neuronsImportant componentControl eggsElectrical afterdischargeNeuroactive peptidesAMPEggsCorrelated behaviorNeuronsAplysiaPeptides
1980
Purification and primary structure of two neuroactive peptides that cause bag cell afterdischarge and egg-laying in Aplysia
Heller E, Kaczmarek L, Hunkapiller M, Hood L, Strumwasser F. Purification and primary structure of two neuroactive peptides that cause bag cell afterdischarge and egg-laying in Aplysia. Proceedings Of The National Academy Of Sciences Of The United States Of America 1980, 77: 2328-2332. PMID: 6929554, PMCID: PMC348708, DOI: 10.1073/pnas.77.4.2328.Peer-Reviewed Original ResearchConceptsBag cell neuronsEgg-laying hormoneCell neuronsNeuroactive peptidesBag cell afterdischargePeptide BPleuroabdominal connectivesAbdominal ganglionRecipient animalsNeuronal receptorsHead gangliaVitro recordingsReproductive tractBag cellsGangliaAtrial glandNeuronsAtrial gland peptidesHormoneGlandGland peptideAgarose gel filtrationPeptide AAplysiaPro-Phe