2021
Association Between Hyperoxia, Supplemental Oxygen, and Mortality in Critically Injured Patients
Douin D, Anderson E, Dylla L, Rice J, Jackson C, Wright F, Bebarta V, Schauer S, Ginde A. Association Between Hyperoxia, Supplemental Oxygen, and Mortality in Critically Injured Patients. Critical Care Explorations 2021, 3: e0418. PMID: 34036272, PMCID: PMC8133168, DOI: 10.1097/cce.0000000000000418.Peer-Reviewed Original ResearchIn-hospital mortalityAdult trauma patientsInjured patientsCohort studyRisk scoreTrauma patientsEmergency department arrivalLevel I trauma centerOutcome of in-hospital mortalityICU admissionMechanism of injuryRisk of mortalityRetrospective cohort studyBlunt trauma mechanismHigh oxygen administrationOxygen administrationSecondary outcomesPrimary outcomeOxygen saturationLevel IIIVentilator-free daysHospital-free daysDays of hospitalizationCritically ill patientsPeriod of hyperoxia
2020
Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke
Dylla L, Cushman J, Abar B, Benesch C, Jones C, O'Banion M, Adler D. Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke. The American Journal Of Emergency Medicine 2020, 38: 2125-2129. PMID: 33069547, PMCID: PMC7704903, DOI: 10.1016/j.ajem.2020.07.021.Peer-Reviewed Original ResearchConceptsMean arterial pressureCerebral blood flowHemodynamic profileSupplemental oxygenRetrospective analysisHemodynamic consequencesOxygen saturationPrehospital oxygen saturationAcute strokePeripheral vascular resistanceLevels of supplemental oxygenAcademic comprehensive stroke centerSubjects' medical records.Comprehensive stroke centerClinical characteristicsAcute stroke patientsVascular resistanceArterial pressureMultivariate linear regressionMultivariate analysisImprove stroke outcomesMedical recordsGuidelines-Stroke registryPenumbral tissueBlood flow
2019
Prehospital supplemental oxygen for acute stroke – A retrospective analysis
Dylla L, Adler D, Abar B, Benesch C, Jones C, O'Banion M, Cushman J. Prehospital supplemental oxygen for acute stroke – A retrospective analysis. The American Journal Of Emergency Medicine 2019, 38: 2324-2328. PMID: 31787444, PMCID: PMC7231670, DOI: 10.1016/j.ajem.2019.11.002.Peer-Reviewed Original ResearchConceptsRespiratory complicationsNeurological outcomeSupplemental oxygenRetrospective analysisRate of respiratory complicationsPrehospital oxygen saturationAdministration of supplemental oxygenAssociated with neurological outcomeMultivariate logistic regressionAcademic comprehensive stroke centerSubjects' medical records.Comprehensive stroke centerClinical characteristicsRespiratory compromiseAcute stroke patientsRetrospective natureEligible patientsNo significant increaseImprove stroke outcomesMedical recordsGuidelines-Stroke registryOxygen saturationPenumbral tissuePotential confoundersControl):