2023
Hyperoxia is associated with a greater risk for mortality in critically ill traumatic brain injury patients than in critically ill trauma patients without brain injury
Douin D, Dylla L, Anderson E, Rice J, Jackson C, Bebarta V, Neumann R, Schauer S, Ginde A. Hyperoxia is associated with a greater risk for mortality in critically ill traumatic brain injury patients than in critically ill trauma patients without brain injury. Science Progress 2023, 106: 00368504231160416. PMID: 36879502, PMCID: PMC10450323, DOI: 10.1177/00368504231160416.Peer-Reviewed Original ResearchConceptsTraumatic brain injury statusTraumatic brain injuryIntensive care unitTraumatic brain injury patientsIn-hospital mortalityCritically ill trauma patientsTrauma patientsState Trauma RegistryNon-TBI patientsRisk of mortalityIntensive care unit daysCritically ill TBI patientsRegional trauma centerRetrospective cohort studyIntensive care unit length of stayLength of stayBrain injuryIntensive care unit lengthTrauma registryInjured adultsSecondary analysisBrain injury patientsCohort studyPatient observationSecondary outcomes
2021
A quasiexperimental study of targeted normoxia in critically ill trauma patients
Dylla L, Anderson E, Douin D, Jackson C, Rice J, Schauer S, Neumann R, Bebarta V, Wright F, Ginde A. A quasiexperimental study of targeted normoxia in critically ill trauma patients. Journal Of Trauma And Acute Care Surgery 2021, 91: s169-s175. PMID: 33797494, PMCID: PMC9709909, DOI: 10.1097/ta.0000000000003177.Peer-Reviewed Original ResearchConceptsCritically ill trauma patientsPostintervention subjectsPostintervention periodTrauma patientsTargeted normoxiaIntervention increased adherenceSupplemental oxygenChronic Health Evaluation II scoreEmergency department arrivalNeurosurgical intensive care unitMilitary trauma patientsIntensive care unitCOnsensus-basedQuasiexperimental studyPostinterventionLevels of FiO2Acute PhysiologyPatient timeII scoreClinical outcomesMm HgTherapeutic/care managementAvoidance of hypoxiaReduce morbidityPrimary outcome