2007
NAC1 Regulates the Recruitment of the Proteasome Complex into Dendritic Spines
Shen H, Korutla L, Champtiaux N, Toda S, LaLumiere R, Vallone J, Klugmann M, Blendy J, Mackler S, Kalivas P. NAC1 Regulates the Recruitment of the Proteasome Complex into Dendritic Spines. Journal Of Neuroscience 2007, 27: 8903-8913. PMID: 17699672, PMCID: PMC6672176, DOI: 10.1523/jneurosci.1571-07.2007.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBicucullineCell Cycle ProteinsCells, CulturedCerebral CortexCullin ProteinsCysteine Proteinase InhibitorsDendritic SpinesEmbryo, MammalianGABA AntagonistsGreen Fluorescent ProteinsIntracellular Signaling Peptides and ProteinsLeupeptinsMiceMice, KnockoutNerve Tissue ProteinsNeuronsProteasome Endopeptidase ComplexProtein TransportRatsRepressor ProteinsRNA-Binding ProteinsTransfectionUbiquitinConceptsUbiquitin-proteasome systemDendritic spinesPostsynaptic densityProteolysis machineryProteasome complexTranscriptional proteinsProteasomeGene deletionSynaptic proteinsProteinCortical neuronsSynaptic remodelingSynaptic activitySynaptic plasticityBicucullinePotential missing linkRecruitmentSpineNeuronsNaC1Progressive accumulationMov34CullinMachineryProteolysis
2005
The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal‐like cultures
Korutla L, Wang P, Mackler S. The POZ/BTB protein NAC1 interacts with two different histone deacetylases in neuronal‐like cultures. Journal Of Neurochemistry 2005, 94: 786-793. PMID: 16033423, DOI: 10.1111/j.1471-4159.2005.03206.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBlotting, WesternButyratesCells, CulturedEnzyme InhibitorsGene Expression RegulationHippocampusHistone DeacetylasesHumansHydroxamic AcidsImmunoprecipitationMiceNerve Tissue ProteinsNeuroblastomaNeuronsPlasmidsProtein BindingProtein IsoformsRatsRepressor ProteinsTranscription, GeneticTransfectionTwo-Hybrid System TechniquesConceptsPOZ/BTB proteinProtein-protein interactionsBTB proteinsHistone deacetylasesPOZ domainTwo-hybridGlutathione S-transferase pulldownRecruit histone deacetylasesDifferent histone deacetylasesTranscriptional repressionGST pulldownSNAC1Histone deacetylase inhibitionCorepressorDeacetylasesRepressionDeacetylase inhibitionProteinPulldownHDAC-3NaC1MSin3ANucleus accumbensCNS regionsCoimmunoprecipitation