Temporal lobe volume in panic disorder — a quantitative magnetic resonance imaging study
Vythilingam M, Anderson E, Goddard A, Woods S, Staib L, Charney D, Bremner J. Temporal lobe volume in panic disorder — a quantitative magnetic resonance imaging study. Psychiatry Research 2000, 99: 75-82. PMID: 10963983, DOI: 10.1016/s0925-4927(00)00055-x.Peer-Reviewed Original ResearchConceptsTemporal lobe volumePanic disorderTemporal lobeMagnetic resonance imagingControl subjectsHealthy subjectsLobe volumeSmaller temporal lobe volumeNormal hippocampal volumesMagnetic resonance imaging studyHealthy control subjectsRight temporal lobeQuantitative magnetic resonance imaging studyQuantitative MRI measuresWhole brain volumeResonance imaging studyHippocampal volumeBrain changesMRI measuresBrain volumeWhole brainPatientsQualitative abnormalitiesResonance imagingImaging studiesSPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder
Bremner J, Innis R, White T, Fujita M, Silbersweig D, Goddard A, Staib L, Stern E, Cappiello A, Woods S, Baldwin R, Charney D. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biological Psychiatry 2000, 47: 96-106. PMID: 10664825, DOI: 10.1016/s0006-3223(99)00188-2.Peer-Reviewed Original ResearchConceptsBenzodiazepine receptor bindingBenzodiazepine receptor functionPanic disorder patientsBenzodiazepine receptorsPanic disorderReceptor bindingDisorder patientsPanic attacksReceptor functionPrefrontal cortexSingle photon emissionStatistical parametric mappingGABAergic transmissionHealthy controlsFrontal cortexLeft hippocampusAnimal modelsComparison subjectsPatientsChronic stressPanic anxietyTomography imagingParametric mappingCortexSpecific decrease