2020
Unstimulated, Serum-free Cultures of Retinal Pigment Epithelium Excrete Large Mounds of Drusen-like Deposits
Chen X, Singh D, Adelman RA, Rizzolo LJ. Unstimulated, Serum-free Cultures of Retinal Pigment Epithelium Excrete Large Mounds of Drusen-like Deposits. Current Eye Research 2020, 45: 1390-1394. PMID: 32202447, DOI: 10.1080/02713683.2020.1740744.Peer-Reviewed Original ResearchMeSH KeywordsActinsApolipoproteins ECalciumCell Culture TechniquesCell LineCell ProliferationCoculture TechniquesCulture Media, Serum-FreeElectric ImpedanceHumansInduced Pluripotent Stem CellsLipid MetabolismRetinal DrusenRetinal Pigment EpitheliumStem CellsTight JunctionsTissue Inhibitor of Metalloproteinase-3VitronectinConceptsRetinal pigment epithelium
2006
Effects of Culture Conditions on Heterogeneity and the Apical Junctional Complex of the ARPE-19 Cell Line
Luo Y, Zhuo Y, Fukuhara M, Rizzolo LJ. Effects of Culture Conditions on Heterogeneity and the Apical Junctional Complex of the ARPE-19 Cell Line. Investigative Ophthalmology & Visual Science 2006, 47: 3644-3655. PMID: 16877439, DOI: 10.1167/iovs.06-0166.Peer-Reviewed Original ResearchCell Culture TechniquesCell Membrane PermeabilityCytoskeletal ProteinsElectric ConductivityElectric ImpedanceElectrophysiologyHorseradish PeroxidaseHumansImmunoblottingImmunohistochemistryMembrane ProteinsMicroscopy, FluorescenceOccludinPigment Epithelium of EyeReverse Transcriptase Polymerase Chain ReactionTight Junctions
1997
Differentiation and Transdifferentiation of the Retinal Pigment Epithelium
Zhao S, Rizzolo L, Barnstable C. Differentiation and Transdifferentiation of the Retinal Pigment Epithelium. International Review Of Cytology 1997, 171: 225-266. PMID: 9066129, DOI: 10.1016/s0074-7696(08)62589-9.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumCell type-specific moleculesDifferent expression patternsGrowth factorLoss of polarityTranscription factorsEmbryonic developmentLoss of expressionRetinal cell typesExpression patternsPrE cellsFibroblast growth factorBasic fibroblast growth factorPigment epitheliumCell typesRod photoreceptorsUnique moleculesOcular metabolismRPE layerMonolayer culturesWide arrayExpressionCellsMammalsMolecules