2017
Disruption of Brain–Heart Coupling in Sepsis
Admiraal MM, Gilmore EJ, Van Putten MJAM, Zaveri HP, Hirsch LJ, Gaspard N. Disruption of Brain–Heart Coupling in Sepsis. Journal Of Clinical Neurophysiology 2017, 34: 413-420. PMID: 28520632, DOI: 10.1097/wnp.0000000000000381.Peer-Reviewed Original Research
2015
Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring
Gilmore EJ, Gaspard N, Choi HA, Cohen E, Burkart KM, Chong DH, Claassen J, Hirsch LJ. Acute brain failure in severe sepsis: a prospective study in the medical intensive care unit utilizing continuous EEG monitoring. Intensive Care Medicine 2015, 41: 686-694. PMID: 25763756, DOI: 10.1007/s00134-015-3709-1.Peer-Reviewed Original ResearchConceptsNonconvulsive seizuresSevere sepsisEEG reactivityPeriodic dischargesLate seizuresSOFA scoreAPACHE IIFunctional outcomeContinuous sedationHigh riskLower riskMedical intensive care unitLong-term cognitive outcomesPresence of sedationAPACHE II scoreGood functional outcomeNonconvulsive status epilepticusIntensive care unitContinuous EEG monitoringAcute brain failureAcademic medical centerNew epilepsyII scoreClinical seizuresMedical ICU
2009
Continuous electroencephalography in the medical intensive care unit*
Oddo M, Carrera E, Claassen J, Mayer SA, Hirsch LJ. Continuous electroencephalography in the medical intensive care unit*. Critical Care Medicine 2009, 37: 2051-2056. PMID: 19384197, DOI: 10.1097/ccm.0b013e3181a00604.Peer-Reviewed Original ResearchConceptsContinuous electroencephalography monitoringPeriodic epileptiform dischargesMajority of patientsElectrographic seizuresRetrospective studyMedical intensive care unit patientsIntensive care unit admissionMedical intensive care unitIntensive care unit patientsPeriodic dischargesAcute neurologic conditionsPrimary admission diagnosisCare unit admissionPercent of patientsAcute neurologic injuryCare unit patientsIntensive care unitOnly significant predictorUnit admissionAdmission diagnosisICU admissionMICU patientsHospital dischargeNeurologic injurySeptic patients