2022
Developing a Standardized Approach to Grading the Level of Brain Dysfunction on EEG
Dhakar MB, Sheikh ZB, Desai M, Desai RA, Sternberg EJ, Popescu C, Baron-Lee J, Rampal N, Hirsch LJ, Gilmore EJ, Maciel CB. Developing a Standardized Approach to Grading the Level of Brain Dysfunction on EEG. Journal Of Clinical Neurophysiology 2022, 40: 553-561. PMID: 35239553, DOI: 10.1097/wnp.0000000000000919.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain DiseasesCritical CareElectroencephalographyHumansObserver VariationSurveys and QuestionnairesConceptsCerebral dysfunctionCritical Care EEG Monitoring Research ConsortiumInterrater agreementGrading scaleStandardized approachDegree of dysfunctionKappa statisticsStandardized grading scalePosterior dominant rhythmElectroencephalogram (EEG) background activityLevel of dysfunctionOverall interrater agreementNeuromonitoring toolsFleiss kappa statisticEEG findingsBrain dysfunction
2021
The rescue therapy in epilepsy project Part 2: Insights from people with epilepsy and families on expert-derived preferred practices
Shafer PO, Santilli N, Buchhalter J, Gilchrist B, Kukla A, French JA, Hirsch LJ. The rescue therapy in epilepsy project Part 2: Insights from people with epilepsy and families on expert-derived preferred practices. Epilepsy & Behavior 2021, 125: 108444. PMID: 34839243, DOI: 10.1016/j.yebeh.2021.108444.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCaregiversEpilepsyHealth PersonnelHumansSeizuresSurveys and Questionnaires
2018
EEG Reactivity Evaluation Practices for Adult and Pediatric Hypoxic-Ischemic Coma Prognostication in North America
Amorim E, Gilmore EJ, Abend NS, Hahn CD, Gaspard N, Herman ST, Hirsch LJ, Lee JW, Cash SS, Westover MB. EEG Reactivity Evaluation Practices for Adult and Pediatric Hypoxic-Ischemic Coma Prognostication in North America. Journal Of Clinical Neurophysiology 2018, 35: 510-514. PMID: 30216207, PMCID: PMC6424574, DOI: 10.1097/wnp.0000000000000517.Peer-Reviewed Original ResearchConceptsCardiac arrest prognosticationAcademic hospitalCritical Care EEG Monitoring Research ConsortiumNail bed pressureLight tactile stimuliMajority of hospitalsNeurodiagnostic technologistsPercent of respondentsPediatric hospitalMultiple-choice surveyPractice patternsEEG reactivityNational guidelinesComa prognosticationHospitalProcedure modalitiesReactivity testingPrognosticationEEG amplitudeMean numberTactile stimuliResearch ConsortiumSubstantial variabilityReactivity evaluationHypothermia
2017
The importance of early immunotherapy in patients with faciobrachial dystonic seizures
Thompson J, Bi M, Murchison AG, Makuch M, Bien CG, Chu K, Farooque P, Gelfand JM, Geschwind MD, Hirsch LJ, Somerville E, Lang B, Vincent A, Leite MI, Waters P, Irani SR, Dogan-Onugoren M, Rae-Grant A, Illes Z, Szots M, Malter M, Widman G, Surges R, Archibald N, Reid J, Duncan C, Richardson A, Lilleker J, Iorio R, Blaabjerg M, Abeler K, Shin Y. The importance of early immunotherapy in patients with faciobrachial dystonic seizures. Brain 2017, 141: 348-356. PMID: 29272336, PMCID: PMC5837230, DOI: 10.1093/brain/awx323.Peer-Reviewed Original ResearchMeSH KeywordsADAM ProteinsAdultAgedAged, 80 and overAnalysis of VarianceAntibodiesAnticonvulsantsCognition DisordersDisabled PersonsFemaleFlow CytometryFollow-Up StudiesGreen Fluorescent ProteinsHEK293 CellsHumansImmunotherapyIntracellular Signaling Peptides and ProteinsLimbic EncephalitisMaleMiddle AgedNerve Tissue ProteinsProtein TransportProteinsRetrospective StudiesSeizuresSurveys and QuestionnairesTransfectionYoung AdultConceptsFaciobrachial dystonic seizuresDystonic seizuresCognitive impairmentAddition of immunotherapySerum sodium levelsNormal brain MRIEarly immunotherapyLGI1 antibodiesLimbic encephalitisEpileptogenic mechanismsConsecutive patientsAntiepileptic drugsNormal patientsBrain MRIPatientsSodium levelsImmunotherapyIgG1 antibodiesSeizuresNormal cognitionImpairmentEarly cessationCessationAntibodiesComplex internalization