2019
Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs
Quraishi IH, Mercier MR, Skarpaas TL, Hirsch LJ. Early detection rate changes from a brain‐responsive neurostimulation system predict efficacy of newly added antiseizure drugs. Epilepsia 2019, 61: 138-148. PMID: 31849045, PMCID: PMC7003822, DOI: 10.1111/epi.16412.Peer-Reviewed Original ResearchConceptsPositive predictive valueEpisode startsLonger episodesSystem patientsPredictive valueFirst weekLong-term treatment trialsBrain-responsive neurostimulationSingle epilepsy centerSingle-center cohortRefractory focal epilepsyGreater reductionMedication adjustmentsClinical improvementClinical responseSeizure frequencyAntiseizure drugsCenter cohortMulticenter cohortEpilepsy centersMedication trialsEffective medicationsEfficacy measuresTreatment trialsFocal epilepsy
2002
Nonconvulsive Status Epilepticus after Subarachnoid Hemorrhage
Dennis LJ, Claassen J, Hirsch LJ, Emerson RG, Connolly ES, Mayer SA. Nonconvulsive Status Epilepticus after Subarachnoid Hemorrhage. Neurosurgery 2002, 51: 1136. PMID: 12383358, DOI: 10.1097/00006123-200211000-00006.Peer-Reviewed Original ResearchConceptsNonconvulsive status epilepticusAneurysmal subarachnoid hemorrhageSubarachnoid hemorrhageCEEG monitoringUnexplained comaNeurological deteriorationStatus epilepticusRefractory nonconvulsive status epilepticusNeurological intensive care unitProphylactic anticonvulsant therapyHours of hospitalizationContinuous electroencephalographic monitoringIntensive care unitAnticonvulsant administrationHospital seizuresAnticonvulsant therapyCerebral edemaClinical improvementHess gradeCare unitClinical featuresComatose patientsElectrographic seizuresVentricular drainageMidazolam therapy