2023
Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up
Becerra L, Gavrieli A, Khan F, Novak P, Lioutas V, Ngo L, Novak V, Mantzoros C. Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. Clinical Nutrition 2023, 42: 825-834. PMID: 37084469, PMCID: PMC10330069, DOI: 10.1016/j.clnu.2023.04.008.Peer-Reviewed Original ResearchConceptsBody mass indexType 2 diabetesIntranasal insulinSecondary outcomesFood intakeBody compositionType 2 diabetes trialsOlder adultsPlacebo-controlled studyPlacebo-controlled trialDiabetes (ACCORD) trialPrimary outcomeIntervention visitsMass indexBody fatAnthropometric measuresAnimal studiesBody weightHigh dosesInteraction of treatmentEnergy homeostasisDiabetesInsulinWeight lossAppetite
2021
719-P: Caloric Intake, Appetite, and Body Composition Outcomes of Long-Term Intranasal Insulin (INI) Administration: A Substudy of the Memory Advancement by INI in Type 2 Diabetes (MemAID) Study
BECERRA L, KHAN F, NGO L, NOVAK V, MANTZOROS C, GAVRIELI A, UPADHYAY J. 719-P: Caloric Intake, Appetite, and Body Composition Outcomes of Long-Term Intranasal Insulin (INI) Administration: A Substudy of the Memory Advancement by INI in Type 2 Diabetes (MemAID) Study. Diabetes 2021, 70 DOI: 10.2337/db21-719-p.Peer-Reviewed Original ResearchType 2 diabetesSecondary outcomesSpouse/partnerCaloric intakeFood intakeAnthropometric measuresBody compositionIntranasal insulin administrationBody composition outcomesType 2 Diabetes StudyWeeks of treatmentNovo NordiskWorld Health OrganizationAdvisory PanelPrimary outcomeIntervention visitsInsulin resistanceKidney diseaseDiabetes StudyInsulin administrationBody fatBlind trialAnimal studiesComposition outcomesDrug Administration