2019
Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study
Krishnamurti L, Neuberg D, Sullivan K, Kamani N, Abraham A, Campigotto F, Zhang W, Dahdoul T, De Castro L, Parikh S, Bakshi N, Haight A, Hassell K, Loving R, Rosenthal J, Smith S, Smith W, Spearman M, Stevenson K, Wu C, Wiedl C, Waller E, Walters M. Bone marrow transplantation for adolescents and young adults with sickle cell disease: Results of a prospective multicenter pilot study. American Journal Of Hematology 2019, 94: 446-454. PMID: 30637784, PMCID: PMC6542639, DOI: 10.1002/ajh.25401.Peer-Reviewed Original ResearchConceptsSevere sickle cell diseaseBone marrow transplantationEvent-free survivalSickle cell diseaseMarrow transplantationCell diseaseElevated tricuspid regurgitant jet velocityRegular red blood cell transfusionsSevere SCDDonor bone marrow transplantationOne-year overall survivalSecond bone marrow transplantationTricuspid regurgitant jet velocityRed blood cell transfusionProspective multicenter pilot studyDeveloped chronic GVHDHost disease (GVHD) prophylaxisStable donor chimerismAcute chest syndromeSecondary graft failureBlood cell transfusionHealth-related qualityPhysical function domainProspective clinical trialsRegurgitant jet velocity
2015
Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease
Walters M, De Castro L, Sullivan K, Krishnamurti L, Kamani N, Bredeson C, Neuberg D, Hassell K, Farnia S, Campbell A, Petersdorf E. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease. Transplantation And Cellular Therapy 2015, 22: 207-211. PMID: 26500093, PMCID: PMC5031360, DOI: 10.1016/j.bbmt.2015.10.017.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnemia, Sickle CellChildHematopoietic Stem Cell TransplantationHistocompatibility TestingHumansQuality of LifeRisk FactorsSiblingsTransplantation ConditioningConceptsHematopoietic cell transplantationSickle cell diseaseCell transplantationCell diseaseSurvival rateEvent-free survival rateTransplant-related complicationsOverall survival rateMarrow Transplant RegistryMarrow Transplant ResearchRisk of mortalityLong-term qualityRate of survivalNontransplant cohortHost diseaseTransplant RegistryOverall survivalProspective trialInternational BloodTransplant ResearchEuropean BloodMortality riskSuitable donorTherapeutic valueStrong recommendations
2003
Availability of unrelated donors for hematopoietic stem cell transplantation for hemoglobinopathies
Krishnamurti L, Abel S, Maiers M, Flesch S. Availability of unrelated donors for hematopoietic stem cell transplantation for hemoglobinopathies. Bone Marrow Transplantation 2003, 31: 547-550. PMID: 12692619, DOI: 10.1038/sj.bmt.1703887.Peer-Reviewed Original ResearchMeSH KeywordsAnemia, Sickle CellCohort StudiesCord Blood Stem Cell TransplantationHematopoietic Stem Cell TransplantationHistocompatibility TestingHumansRegistriesThalassemiaTissue DonorsConceptsHematopoietic stem cell transplantationNational Marrow Donor ProgramStem cell transplantationUnrelated donorsHemoglobinopathy patientsCell transplantationThalassemia patientsURD HSCTLife-threatening blood diseaseSickle cell disease patientsUnrelated bone marrow donorsUmbilical cord blood unitsHLA-identical siblingsOnly curative optionCord blood unitsBone marrow donorsCurative optionPreparative regimensHLA matchDisease patientsPotential HLAMarrow donorsNMDP RegistryPatientsVolunteer donors