2015
Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality
Goel R, Ness P, Takemoto C, Krishnamurti L, King K, Tobian A. Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality. Blood 2015, 125: 1470-1476. PMID: 25588677, PMCID: PMC4342358, DOI: 10.1182/blood-2014-10-605493.Peer-Reviewed Original ResearchConceptsImmune thrombocytopenic purpuraThrombotic thrombocytopenic purpuraAcute myocardial infarctionPlatelet transfusionsArterial thrombosisVenous thrombosisHigher oddsHospital mortalityThrombocytopenic purpuraGender-adjusted odds ratioPlatelet transfusion practicesNationwide Inpatient SampleConsumptive disordersHIT patientsTransfusion practiceInpatient SampleMyocardial infarctionClinical severityOdds ratioTransfusionThrombosisPrimary mediatorMortalityLittle dataPurpura
2010
Platelet Transfusions In Patients with Immune Thrombocytopenic Purpura (ITP) – Evaluation of the Current Nationwide Inpatient Hospital Practices.
Tran L, Goel R, Krishnamurti L. Platelet Transfusions In Patients with Immune Thrombocytopenic Purpura (ITP) – Evaluation of the Current Nationwide Inpatient Hospital Practices. Blood 2010, 116: 3809. DOI: 10.1182/blood.v116.21.3809.3809.Peer-Reviewed Original ResearchImmune thrombocytopenic purpuraManagement of ITPMajor bleedsPlatelet transfusionsHospital dischargeMortality rateGastrointestinal bleedITP patientsIntracranial hemorrhageNationwide Inpatient Sample 2007Payer inpatient databasePlatelet transfusion practicesInternational consensus guidelinesImproved mortality ratesStratified probability sampleU.S. community hospitalsThrombocytopenic purpuraPlatelet countTransfusion practiceConsensus guidelinesInpatient DatabaseMean ageSevere hemorrhageCommunity hospitalPediatric discharges