2019
Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis
Gupta A, Hannan A, Maini R, Bitner S, Stone S, Regmi M, Tobian A, Josephson C, Krishnamurti L, Takemoto C, Goel R. Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Representative Estimates and a Comparative Analysis. Blood 2019, 134: 4711. DOI: 10.1182/blood-2019-123161.Peer-Reviewed Original ResearchCongestive heart failureNationwide Inpatient SampleMedian hospital chargesHepatitis CMedian ageHIV/AIDSHospital dischargeInpatient mortalityHeart failureCommon diagnosisHealthcare utilizationHaemophilia patientsHospital chargesMortality rateHemophilia AUtilization Project Nationwide Inpatient SampleYounger ageCommon discharge diagnosesMost hemophilia patientsNon-bleeding complicationsInpatient mortality rateHepatitis C casesCentral line infectionsCoronary artery diseaseInsurance coverage
2012
Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates
GOEL R, KRISHNAMURTI L. Mortality, health care utilization and associated diagnoses in hospitalized patients with haemophilia in the United States: first reported nationwide estimates. Haemophilia 2012, 18: 688-692. PMID: 22500777, DOI: 10.1111/j.1365-2516.2012.02774.x.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleCentral line infectionsHospital mortalityHospital dischargeLine infectionsHemophilia AMean hospital chargesCause of hospitalizationHealth care utilizationGeneral male populationDiagnosis of hemophiliaAge-related illnessesStratified probability sampleHepatitis CRespiratory failureHeart failureIntraventricular hemorrhageMedian ageAge of mortalityCare utilizationHospital chargesIntracranial hemorrhageNeonatal periodPediatric deathsHepatic coma
2011
Clinical Predictors of All-Cause In-Hospital Mortality In Patients with Sickle Cell Disease in the United States- First Reported Results From A Nationally Representative Sample
Goel R, Gupta A, Krishnamurti L. Clinical Predictors of All-Cause In-Hospital Mortality In Patients with Sickle Cell Disease in the United States- First Reported Results From A Nationally Representative Sample. Blood 2011, 118: 339. DOI: 10.1182/blood.v118.21.339.339.Peer-Reviewed Original ResearchSickle cell diseaseHospital mortality rateIn-Hospital MortalityClinical predictorsCell diseaseHospital mortalityHospital dischargeClinical factorsIndependent predictorsNationally Representative SampleRelated hospitalizationsSCD patientsExchange transfusionMortality rateICD-9-CM diagnosis codesNationwide Inpatient Sample databaseMultivariable logistic regression modelDiagnosis of SCDAcute chest syndromePredictors of mortalityRed cell transfusionDevelopment of sepsisPatients' socioeconomic statusMultivariable logistic regressionSignificant independent predictors
2010
Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States
Gupta A, Krishnamurti L. Burden of In-Hospital Care of Thrombotic Microangiopathies In the United States. Blood 2010, 116: 2559. DOI: 10.1182/blood.v116.21.2559.2559.Peer-Reviewed Original ResearchNationwide Inpatient SampleThrombotic microangiopathyHealth care utilizationRelated hospital admissionsHealthcare utilizationHospital dischargeHospital admissionCare utilizationHospital chargesTherapeutic plasmapheresisAge groupsFrequent healthcare encountersIn-Hospital CarePayer inpatient databaseClinical Modification codesAverage hospital chargesBurden of careNational dataFirst national dataStratified probability sampleU.S. community hospitalsTotal hospitalizationsFrequent hospitalizationsInpatient DatabaseMean durationPlatelet Transfusions In Patients with Immune Thrombocytopenic Purpura (ITP) – Evaluation of the Current Nationwide Inpatient Hospital Practices.
Tran L, Goel R, Krishnamurti L. Platelet Transfusions In Patients with Immune Thrombocytopenic Purpura (ITP) – Evaluation of the Current Nationwide Inpatient Hospital Practices. Blood 2010, 116: 3809. DOI: 10.1182/blood.v116.21.3809.3809.Peer-Reviewed Original ResearchImmune thrombocytopenic purpuraManagement of ITPMajor bleedsPlatelet transfusionsHospital dischargeMortality rateGastrointestinal bleedITP patientsIntracranial hemorrhageNationwide Inpatient Sample 2007Payer inpatient databasePlatelet transfusion practicesInternational consensus guidelinesImproved mortality ratesStratified probability sampleU.S. community hospitalsThrombocytopenic purpuraPlatelet countTransfusion practiceConsensus guidelinesInpatient DatabaseMean ageSevere hemorrhageCommunity hospitalPediatric discharges
2009
Current Epidemiology and Hospitalization Characteristics for Acute Chest Syndrome: A Nationally Representative Survey.
Goel R, Viswanathan P, Krishnamurti L. Current Epidemiology and Hospitalization Characteristics for Acute Chest Syndrome: A Nationally Representative Survey. Blood 2009, 114: 4608. DOI: 10.1182/blood.v114.22.4608.4608.Peer-Reviewed Original ResearchAcute chest syndromeSickle cell diseaseSCD patientsChest syndromeHospital mortalityHospital dischargeCommon complicationRelated hospitalizationsExchange transfusionMechanical ventilationDischarge diagnosisAge groupsICD-9-CM diagnosis codesNationwide Inpatient Sample databaseHigher hospital chargesMean lengthCost of hospitalizationYears age groupMajority of deathsCause of mortalityHigher mean chargesNationally Representative SurveyStratified probability sampleHealth care qualityU.S. community hospitals