Risk Factors for Death in 632 Patients with Sickle Cell Anemia in the United States and United Kingdom
Gladwin M, Barst R, Gibbs J, Hildesheim M, Sachdev V, Nouraie M, Hassell K, Little J, Schraufnagel D, Krishnamurti L, Novelli E, Girgis R, Zhang Y, Morris C, Rosenzweig E, Badesch D, Lanzkron S, Castro O, Taylor J, Goldsmith J, Gordeuk V, Kato G, Machado R. Risk Factors for Death in 632 Patients with Sickle Cell Anemia in the United States and United Kingdom. Blood 2012, 120: 3240. DOI: 10.1182/blood.v120.21.3240.3240.Peer-Reviewed Original ResearchTricuspid regurgitant jet velocityHigher tricuspid regurgitant jet velocityProportional hazards regression analysisHigher NT-proBNPUnadjusted hazard ratioNT-proBNPHazards regression analysisSickle cell diseasePulmonary hypertensionRisk factorsGlaxo Smith KlineAspartate aminotransferaseHazard ratioCell diseaseCox proportional hazards regression analysisMean pulmonary artery pressureSix-minute walk distanceSickle cell disease patientsPopulation screening studiesPulmonary artery pressureRight heart catheterizationRegurgitant jet velocityRisk of deathDoppler echocardiographic measurementsScreening study