2014
Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body
Talbert-Slagle K, Atkins KE, Yan KK, Khurana E, Gerstein M, Bradley EH, Berg D, Galvani AP, Townsend JP. Cellular Superspreaders: An Epidemiological Perspective on HIV Infection inside the Body. PLOS Pathogens 2014, 10: e1004092. PMID: 24811311, PMCID: PMC4014458, DOI: 10.1371/journal.ppat.1004092.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2013
A Single Amino Acid Substitution Converts a Transmembrane Protein Activator of the Platelet-derived Growth Factor β Receptor into an Inhibitor*
Petti LM, Talbert-Slagle K, Hochstrasser ML, DiMaio D. A Single Amino Acid Substitution Converts a Transmembrane Protein Activator of the Platelet-derived Growth Factor β Receptor into an Inhibitor*. Journal Of Biological Chemistry 2013, 288: 27273-27286. PMID: 23908351, PMCID: PMC3779723, DOI: 10.1074/jbc.m113.470054.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SubstitutionAnimalsBovine papillomavirus 1CattleCell LineCell Transformation, ViralEnzyme ActivatorsFibroblastsHumansMaleMiceMutation, MissenseOncogene Proteins v-sisOncogene Proteins, ViralPhosphorylationProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor betaSignal TransductionConceptsTransmembrane domainTransmembrane proteinPlatelet-derived growth factor β receptorLimited sequence similarityGrowth factor β receptorParticular tyrosine residueLigand-independent mannerSequence similarityGenetic evidenceGrowth factor receptorE5 proteinOncogenic transformationWild typeProtein activatorViral homologueTyrosine residuesE5 bindsProtein inhibitorPDGFβRV-sisPDGFβ receptorBovine papillomavirusFactor receptorNonidentical sitesCell proliferation