2024
Pain during Cesarean Delivery: We Can and Must Do Better
Zakowski M, Fardelmann K, Hofkamp M. Pain during Cesarean Delivery: We Can and Must Do Better. Anesthesiology 2024, 140: 1236-1237. PMID: 38597801, DOI: 10.1097/aln.0000000000004968.Peer-Reviewed Original Research
2022
Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report
Ackerman-Banks C, Fardelmann K, Lam D, Simmons M, Elder R, Matouk C, Campbell K. Unrepaired Maternal Vein of Galen Malformation in Pregnancy: A Case Report. A&A Practice 2022, 16: e01634. PMID: 36599040, DOI: 10.1213/xaa.0000000000001634.Peer-Reviewed Case Reports and Technical NotesConceptsGalen malformationMaternal veinPregnant patientsCesarean deliveryNeuraxial analgesiaTerm neonatesAnesthetic managementHeart failureCardiac failureVentricular dilationIntracranial hemorrhageCase reportCare centerDevelopmental delayPatientsPregnancyLesionsMalformationsVeinUnrepaired lesionsDeliveryAnalgesiaEmbolizationHemorrhageNeonatesComparison between the Rotational Thromboelastometry (ROTEM) Delta device against the Cartridge-based Thromboelastography 6s and Quantra in a healthy third trimester pregnant cohort
Gonzalez-Fiol A, Fardelmann KL, Yanez D, Salimi N, Mancini P, Alian A. Comparison between the Rotational Thromboelastometry (ROTEM) Delta device against the Cartridge-based Thromboelastography 6s and Quantra in a healthy third trimester pregnant cohort. Journal Of Clinical Monitoring And Computing 2022, 37: 267-273. PMID: 35904696, DOI: 10.1007/s10877-022-00888-0.Peer-Reviewed Original Research
2021
Does Anesthesia and Surgery During Pregnancy Really Affect Learning and Behavior in the Offspring: The Holy Grail in Anesthesiology Research
Fardelmann K, Gaiser R. Does Anesthesia and Surgery During Pregnancy Really Affect Learning and Behavior in the Offspring: The Holy Grail in Anesthesiology Research. Anesthesia & Analgesia 2021, 133: 592-594. PMID: 34403387, DOI: 10.1213/ane.0000000000005486.Commentaries, Editorials and Letters
2020
Anesthesia for Obstetric Disasters
Fardelmann KL, Alian AA. Anesthesia for Obstetric Disasters. Advances In Anesthesia 2020, 38: 229-250. PMID: 34106836, DOI: 10.1016/j.aan.2020.09.001.ChaptersConceptsLocal anesthetic systemic toxicityDifficult obstetric airwayAmniotic fluid embolismMaternal cardiac arrestAnesthesia complicationsObstetric airwayObstetric disasterFetal morbidityFetal outcomesHELLP syndromeHypertensive disordersCardiac arrestMaternal mortalityNeuraxial blockadeObstetric anesthesiologistObstetric emergenciesLive birthsSystemic toxicityExpeditious interventionMortalityMorbidityEmbolismComplicationsHemorrhageAirwayPrevalence of aberrant blood pressure readings across two automated intraoperative blood pressure monitoring systems among patients undergoing caesarean delivery.
Schonberger RB, Gonzalez-Fiol A, Fardelmann KL, Bardia A, Michel G, Dai F, Banack T, Alian A. Prevalence of aberrant blood pressure readings across two automated intraoperative blood pressure monitoring systems among patients undergoing caesarean delivery. Blood Pressure Monitoring 2020, 26: 78-83. PMID: 33234814, PMCID: PMC8715608, DOI: 10.1097/mbp.0000000000000495.Peer-Reviewed Original ResearchConceptsBlood pressure readingsCaesarean deliveryBP readingsMultivariable logistic regression analysisPressure readingsCesarean delivery patientsComparable patient cohortsIntraoperative blood pressureRetrospective observational studySame surgical procedurePre-specified covariatesLogistic regression analysisBlood pressureDelivery patientsSimilar patientsPatient cohortSurgical centersBP measurementsBP monitoring systemObservational studyBP monitorInclusion criteriaSurgical proceduresRelative oddsPatientsNitrous oxide analgesia for external cephalic version: A randomized controlled trial
Straube LE, Fardelmann KL, Penwarden AA, Chen F, Harker E, Redmon BF, Li Q, Strauss R, Smith KA. Nitrous oxide analgesia for external cephalic version: A randomized controlled trial. Journal Of Clinical Anesthesia 2020, 68: 110073. PMID: 33017784, DOI: 10.1016/j.jclinane.2020.110073.Peer-Reviewed Original ResearchConceptsExternal cephalic versionNitrous oxide analgesiaCephalic versionNitrous oxide groupOxygen placeboBreech presentationPatient satisfactionDouble-blinded randomized placebo-controlled trialRandomized placebo-controlled trialAnesthesiology physical status IRoutine useIntra-procedural painMean pain scorePlacebo-controlled trialPhysical status IYears of ageMinimal side effectsNitrous oxide/50Analgesic benefitPain scoresSecondary outcomesSingleton pregnanciesStatus IPrimary outcomeNeuraxial anesthesiaSARS-CoV-2 infection of the placenta
Hosier H, Farhadian SF, Morotti RA, Deshmukh U, Lu-Culligan A, Campbell KH, Yasumoto Y, Vogels C, Casanovas-Massana A, Vijayakumar P, Geng B, Odio CD, Fournier J, Brito AF, Fauver JR, Liu F, Alpert T, Tal R, Szigeti-Buck K, Perincheri S, Larsen C, Gariepy AM, Aguilar G, Fardelmann KL, Harigopal M, Taylor HS, Pettker CM, Wyllie AL, Dela Cruz CS, Ring AM, Grubaugh ND, Ko AI, Horvath TL, Iwasaki A, Reddy UM, Lipkind HS. SARS-CoV-2 infection of the placenta. Journal Of Clinical Investigation 2020, 130: 4947-4953. PMID: 32573498, PMCID: PMC7456249, DOI: 10.1172/jci139569.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAbortion, TherapeuticAbruptio PlacentaeAdultBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansMicroscopy, Electron, TransmissionPandemicsPhylogenyPlacentaPneumonia, ViralPre-EclampsiaPregnancyPregnancy Complications, InfectiousPregnancy Trimester, SecondRNA, ViralSARS-CoV-2Viral LoadConceptsSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2SARS-CoV-2 infectionRespiratory syndrome coronavirus 2SARS-CoV-2 invasionMaternal antibody responseSymptomatic COVID-19Second trimester pregnancySyndrome coronavirus 2Coronavirus disease 2019Materno-fetal interfaceDense macrophage infiltratesPlacental abruptionSevere preeclampsiaMacrophage infiltratesSevere morbidityTrimester pregnancyPregnant womenCoronavirus 2Antibody responseBackgroundThe effectsDisease 2019Histological examinationImmunohistochemical assaysPlacentaThe Application of ROTEM in a Parturient With Antiphospholipid Syndrome in the Setting of Anticoagulation for Cesarean Delivery: A Case Report.
Fiol AG, Fardelmann KL, McGuire PJ, Merriam AA, Miller A, Alian A. The Application of ROTEM in a Parturient With Antiphospholipid Syndrome in the Setting of Anticoagulation for Cesarean Delivery: A Case Report. A&A Practice 2020, 14: e01182. PMID: 32224689, DOI: 10.1213/xaa.0000000000001182.Peer-Reviewed Case Reports and Technical NotesConceptsAntiphospholipid syndromeHeparin neutralizationDiagnosis of hemolysisElevated liver enzymesSetting of anticoagulationFresh frozen plasmaPartial thromboplastin timeCesarean deliveryLow plateletsTransfusion managementCase reportFrozen plasmaLiver enzymesThromboplastin timeParturientsSyndromeIntrinsic pathwayAnticoagulationROTEMDiagnosisNeutralizationHeparinAnesthesia for Obstetric Disasters
Fardelmann KL, Alian AA. Anesthesia for Obstetric Disasters. Anesthesiology Clinics 2020, 38: 85-105. PMID: 32008659, DOI: 10.1016/j.anclin.2019.10.005.ChaptersConceptsLocal anesthetic systemic toxicityDifficult obstetric airwayAmniotic fluid embolismMaternal cardiac arrestAnesthesia complicationsObstetric airwayObstetric disasterFetal morbidityFetal outcomesHELLP syndromeHypertensive disordersCardiac arrestMaternal mortalityNeuraxial blockadeObstetric anesthesiologistObstetric emergenciesLive birthsSystemic toxicityExpeditious interventionMortalityMorbidityEmbolismComplicationsHemorrhageAirway