Regulation of human osteoclast development by dendritic cell‐specific transmembrane protein (DC‐STAMP)
Chiu Y, Mensah KA, Schwarz EM, Ju Y, Takahata M, Feng C, McMahon LA, Hicks DG, Panepento B, Keng PC, Ritchlin CT. Regulation of human osteoclast development by dendritic cell‐specific transmembrane protein (DC‐STAMP). Journal Of Bone And Mineral Research 2011, 27: 79-92. PMID: 21987375, PMCID: PMC3304467, DOI: 10.1002/jbmr.531.Peer-Reviewed Original ResearchConceptsDendritic cell-specific transmembrane proteinImmunoreceptor tyrosine-based inhibitory motifOC precursorsInflammatory arthritisTransmembrane proteinSH2 domain-containing tyrosine phosphataseTransmembrane receptor-like proteinErosive inflammatory arthritisCell fusionTumor giant cellsMetabolic bone diseaseReceptor-like proteinDC-STAMP expressionTyrosine-based inhibitory motifCell surface receptorsBone diseaseHuman PBMCsTyrosine phosphataseOsteoclast developmentCytoplasmic tailGiant cellsCellular transformationOC formationOsteoclastogenesisSHP-1