Mediation of nonerosive arthritis in a mouse model of lupus by interferon‐α–stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis
Mensah KA, Mathian A, Ma L, Xing L, Ritchlin CT, Schwarz EM. Mediation of nonerosive arthritis in a mouse model of lupus by interferon‐α–stimulated monocyte differentiation that is nonpermissive of osteoclastogenesis. Arthritis & Rheumatism 2010, 62: 1127-1137. PMID: 20131244, PMCID: PMC2854832, DOI: 10.1002/art.27312.Peer-Reviewed Original ResearchConceptsMyeloid dendritic cellsSystemic lupus erythematosusSerum-induced arthritisNZB xBone erosionDendritic cellsOsteoclast precursorsAntibody titersMouse modelAnti-dsDNA antibody titersDNA antibody titersMicrofocal computed tomographyCytokine interferon-alphaEffects of IFNalphaJaccoud's arthritisNonerosive arthritisSLE diseaseJoint inflammationLupus erythematosusAutoimmune diseasesNZW miceSerum administrationInterferon alphaFocal erosionsSLE monocytes