A New Solution to an Age-old Problem: A Review of Ketamine and Esketamine for Treatment-resistant Depression in Late Life
Balaram K, van Dyck L, Wilkins K, Maruca-Sullivan P. A New Solution to an Age-old Problem: A Review of Ketamine and Esketamine for Treatment-resistant Depression in Late Life. Current Geriatrics Reports 2023, 12: 93-102. DOI: 10.1007/s13670-023-00389-1.Peer-Reviewed Original ResearchTreatment-resistant major depressive disorderUse of ketamineOlder adultsKetamine/esketamineTreatment-resistant depressionAnti-depressant effectsEfficacy of ketamineLate-onset depressionOnset of actionCurrent treatment strategiesLate-life depressionCase series dataMajor depressive disorderTypes of patientsDegree of disabilityPotential long termOpen labelAntidepressant effectsOnset depressionOverall mortalityHealthcare utilizationTreatment algorithmCase reportCaregiver burdenClinical trials