2018
Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia
Reljin N, Zimmer G, Malyuta Y, Shelley K, Mendelson Y, Blehar DJ, Darling CE, Chon KH. Using support vector machines on photoplethysmographic signals to discriminate between hypovolemia and euvolemia. PLOS ONE 2018, 13: e0195087. PMID: 29596477, PMCID: PMC5875841, DOI: 10.1371/journal.pone.0195087.Peer-Reviewed Original ResearchConceptsBlood lossTrauma patientsTraditional vital signsLast time pointBlood pressureHemorrhagic shockCombat casualty careBlood withdrawalHealthy volunteersPhotoplethysmographic recordingsHeart rateBlood volumeEuvolemiaVital signsHypovolemiaPercentage changeTime pointsAbsolute changeCasualty carePatientsBattlefield settingsEarly stagesHemorrhageRecordingsHospital
2016
Ventilation-Induced Modulation of Pulse Oximeter Waveforms
Alian AA, Atteya G, Gaal D, Golembeski T, Smith BG, Dai F, Silverman DG, Shelley K. Ventilation-Induced Modulation of Pulse Oximeter Waveforms. Anesthesia & Analgesia 2016, 123: 346-356. PMID: 27284998, DOI: 10.1213/ane.0000000000001377.Peer-Reviewed Original ResearchConceptsSystolic blood pressureArterial pressure waveformBlood volumeFluid resuscitationBlood pressureOnly systolic blood pressurePressure waveformAirway pressure waveformFinger pulse oximetrySubstantial blood lossDynamic preload indicesVenous blood volumeArterial pressure measurementsArterial waveform parametersP-valuePulse oximeter waveformWilcoxon signed-rank testArterial pressureBlood lossBlood transfusionEarly bleedingPediatric patientsPreload indexHemodynamic dataScoliosis surgery
2014
Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia
Zhu R, Atteya G, Shelley KH, Silverman DG, Alian AA. Analysis of plethysmographic waveform changes induced by beach chair positioning under general anesthesia. Journal Of Clinical Monitoring And Computing 2014, 28: 591-596. PMID: 24420341, DOI: 10.1007/s10877-014-9555-9.Peer-Reviewed Original ResearchConceptsBeach chair positioningVasoactive drugsBlood pressureShoulder surgeryNoninvasive hemodynamic parametersPostoperative cerebral ischemiaMean arterial pressureTidal carbon dioxideBeach chair positionIntermittent blood pressureChair positionWilcoxon signed-rank testPosition surgeryArterial pressureCerebral ischemiaGeneral anesthesiaSigned-rank testHemodynamic parametersRare caseDevastating outcomesHeart rateRespiratory frequencyPatientsSurgeryAmplitude density
2012
Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion?
Phillips J, Belhaj A, Shafqat K, Langford R, Shelley K, Kyriacou P. Modulation of finger photoplethysmographic traces during forced respiration: Venous blood in motion? Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2012, 2012: 3644-3647. PMID: 23366717, DOI: 10.1109/embc.2012.6346756.Peer-Reviewed Original ResearchConceptsVenous oxygen saturationOxygen saturationBlood volumeNegative airway pressureAirway pressureVenous bloodArterial saturationRespiratory modulationHealthy volunteersRespiratory frequencyTissue bedsPilot studyResultant modulationArteryModulationFingerBloodPhotoplethysmographic signalsVolunteers
2006
What Is the Best Site for Measuring the Effect of Ventilation on the Pulse Oximeter Waveform?
Shelley KH, Jablonka DH, Awad AA, Stout RG, Rezkanna H, Silverman DG. What Is the Best Site for Measuring the Effect of Ventilation on the Pulse Oximeter Waveform? Anesthesia & Analgesia 2006, 103: 372-377. PMID: 16861419, DOI: 10.1213/01.ane.0000222477.67637.17.Peer-Reviewed Original ResearchConceptsPositive pressure ventilationPulse oximeter waveformPressure ventilationPlethysmographic waveformEffect of ventilationBlood lossRenal dialysisSpontaneous breathingPlethysmographic dataSurgical proceduresTidal volumeBlood volumeRespiratory rateVentilationPatientsSignificant correlationRespiratory signalPredominant featureImpact of ventilationCardiac pulseSurgeryFingerBreathingDialysis
2001
How Does the Plethysmogram Derived from the Pulse Oximeter Relate to Arterial Blood Pressure in Coronary Artery Bypass Graft Patients?
Awad A, Ghobashy M, Stout R, Silverman D, Shelley K. How Does the Plethysmogram Derived from the Pulse Oximeter Relate to Arterial Blood Pressure in Coronary Artery Bypass Graft Patients? Anesthesia & Analgesia 2001, 93: 1466-1471. PMID: 11726424, DOI: 10.1097/00000539-200112000-00022.Peer-Reviewed Original ResearchConceptsMean blood pressureSystolic blood pressureBlood pressurePulse pressurePulse oximeter waveformCoronary artery bypass graft surgeryCoronary artery bypass graft patientsArtery bypass graft surgeryBypass graft surgeryCoronary artery bypassBypass graft patientsRadial artery blood pressure waveformArterial blood pressureBlood pressure waveformArtery bypassGraft patientsGraft surgeryArterial linePatientsFinger oximeterMean differenceClinical applicabilityPulse oximeterPressure waveformOximeterDifferent Responses of Ear and Finger Pulse Oximeter Wave Form to Cold Pressor Test
Awad A, Ghobashy M, Ouda W, Stout R, Silverman D, Shelley K. Different Responses of Ear and Finger Pulse Oximeter Wave Form to Cold Pressor Test. Anesthesia & Analgesia 2001, 92: 1483-1486. PMID: 11375830, DOI: 10.1097/00000539-200106000-00026.Peer-Reviewed Original ResearchConceptsCold pressor testVasoconstrictive responsePressor testIce water immersionPlethysmographic amplitudeVasoconstrictive effectSympathetic toneContralateral handHealthy volunteersSystemic circulationIRB approvalCold stimuliClinical settingEarSignificant disparitiesSignificant changesSuitable monitorFingerResponseEar signalsWater immersionPlethysmography
1997
Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone
Shelley K, Bosseau Murray W, Chang D. Arterial–Pulse Oximetry Loops: A New Method of Monitoring Vascular Tone. Journal Of Clinical Monitoring 1997, 13: 223-228. PMID: 9269615, DOI: 10.1023/a:1007361020825.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic alpha-AgonistsAnesthesia, IntravenousArteriesBlood PressureBlood VolumeCalibrationCephalometryDose-Response Relationship, DrugEphedrineFemaleFingersForecastingHeart RateHumansHypotensionIntraoperative ComplicationsMeningiomaMiddle AgedMonitoring, PhysiologicOnline SystemsOximetryPhenylephrinePlethysmographySignal Processing, Computer-AssistedVascular ResistanceVasoconstrictor AgentsVasomotor SystemConceptsPulse oximeter waveformVascular resistanceVascular toneVascular compliancePeripheral vascular complianceVascular compliance changesPeripheral vascular resistanceDose-response curveArterial pressureCase reportArterial waveformClinical informationCompliance changesRelative complianceComplianceTonePhenylephrineOff-line calculation
1993
The detection of peripheral venous pulsation using the pulse oximeter as a plethysmograph
Shelley K, Dickstein M, Shulman S. The detection of peripheral venous pulsation using the pulse oximeter as a plethysmograph. Journal Of Clinical Monitoring 1993, 9: 283-287. PMID: 8301336, DOI: 10.1007/bf02886699.Peer-Reviewed Original Research