2021
Variability in utilization of diagnostic imaging tests in patients with symptomatic peripheral artery disease
Derbas LA, Patel KK, Muskula PR, Wang J, Gosch K, Fitridge R, Spertus JA, Smolderen KG. Variability in utilization of diagnostic imaging tests in patients with symptomatic peripheral artery disease. International Journal Of Cardiology 2021, 330: 200-206. PMID: 33581177, DOI: 10.1016/j.ijcard.2021.02.014.Peer-Reviewed Original ResearchMeSH KeywordsDiagnostic ImagingHumansLogistic ModelsOdds RatioPeripheral Arterial DiseaseReferral and ConsultationConceptsPeripheral arterial diseaseMedian odds ratioImaging testsSymptomatic peripheral artery diseaseSymptomatic peripheral arterial diseaseInvasive imaging testsPAQ summary scoreVascular specialty clinicsPatient-level factorsPeripheral artery diseaseDiagnostic imaging testsHierarchical logistic regression modelsLogistic regression modelsMean ABIPAD diagnosisNew onsetPAD symptomsPatient demographicsArtery diseasePatient characteristicsVascular clinicArterial diseaseDisease characteristicsRecent exacerbationReferral rates
2020
Physical Activity After Treatment for Symptomatic Peripheral Artery Disease
Peri-Okonny PA, Patel S, Spertus JA, Jackson EA, Malik AO, Provance J, Mena-Hurtado C, Shishehbor MH, Hijjaji V, Gosch KL, Smolderen K. Physical Activity After Treatment for Symptomatic Peripheral Artery Disease. The American Journal Of Cardiology 2020, 138: 107-113. PMID: 33065083, PMCID: PMC7736254, DOI: 10.1016/j.amjcard.2020.10.011.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnkle Brachial IndexConservative TreatmentEndovascular ProceduresExerciseExercise TherapyFemaleHealth StatusHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIntermittent ClaudicationLeisure ActivitiesLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient SatisfactionPeripheral Arterial DiseasePlatelet Aggregation InhibitorsQuality of LifeSedentary BehaviorSmoking CessationSocial InteractionVascular Surgical ProceduresWorkConceptsPhysical activity levelsPhysical activityInvasive treatmentSymptomatic peripheral artery diseasePeripheral artery diseaseMultivariable logistic regressionAssociation of treatmentActivity levelsMultivariable linear regressionHealth status changesHealth status gainsPAD outcomesArtery diseaseVascular clinicInvasive groupNoninvasive treatmentHealth statusLogistic regressionActivity statusLTPAClaudicationTreatmentPatientsStatus changesAssociation
2017
Prognostic Impact of Subsequent Acute Coronary Syndrome and Unplanned Revascularization on Long‐Term Mortality After an Index Percutaneous Coronary Intervention: A Report From a Japanese Multicenter Registry
Inohara T, Kohsaka S, Miyata H, Sawano M, Ueda I, Maekawa Y, Fukuda K, Jones PG, Cohen DJ, Zhao Z, Spertus JA, Smolderen KG. Prognostic Impact of Subsequent Acute Coronary Syndrome and Unplanned Revascularization on Long‐Term Mortality After an Index Percutaneous Coronary Intervention: A Report From a Japanese Multicenter Registry. Journal Of The American Heart Association 2017, 6: e006529. PMID: 29079567, PMCID: PMC5721753, DOI: 10.1161/jaha.117.006529.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngina, UnstableChi-Square DistributionFemaleHospitals, TeachingHumansIncidenceJapanLogistic ModelsMaleMiddle AgedMyocardial InfarctionPercutaneous Coronary InterventionPropensity ScoreProportional Hazards ModelsRegistriesRetreatmentRisk FactorsTime FactorsTreatment OutcomeConceptsSubsequent acute coronary syndromeAcute coronary syndromePercutaneous coronary interventionPropensity-matched cohortUnplanned coronary revascularizationIndex percutaneous coronary interventionComposite end pointUnplanned revascularizationCoronary revascularizationCoronary syndromeCoronary interventionUnstable anginaClinical trialsEnd pointJapanese multicenter registryLong-term mortalityAcute myocardial infarctionRisk of mortalityProportional hazards modelLong-term survivalJapanese teaching hospitalsCause mortalityMulticenter registryPCI patientsSubsequent survivalSex differences in disease-specific health status measures in patients with symptomatic peripheral artery disease: Data from the PORTRAIT study
Roumia M, Aronow HD, Soukas P, Gosch K, Smolderen KG, Spertus JA, Abbott JD. Sex differences in disease-specific health status measures in patients with symptomatic peripheral artery disease: Data from the PORTRAIT study. Vascular Medicine 2017, 22: 103-109. PMID: 28429659, DOI: 10.1177/1358863x16686408.Peer-Reviewed Original ResearchMeSH KeywordsAgedAnkle Brachial IndexAustraliaChi-Square DistributionCost of IllnessFemaleHealth Status DisparitiesHealth Status IndicatorsHumansIntermittent ClaudicationLinear ModelsLogistic ModelsMaleMental HealthMiddle AgedMultivariate AnalysisNetherlandsPatient SatisfactionPeripheral Arterial DiseasePrognosisProspective StudiesQuality of LifeRisk FactorsSeverity of Illness IndexSex FactorsSocial BehaviorSocioeconomic FactorsSurveys and QuestionnairesUnited StatesConceptsPeripheral artery diseasePeripheral Artery QuestionnaireHealth statusArtery diseaseSymptoms of PADAnkle-brachial index valuesPAD-specific health statusSymptomatic peripheral artery diseaseDisease-specific health status measuresPAQ scoresPeripheral arterial diseaseSex differencesHealth status domainsInternational prospective studyPoor health statusHealth status measuresMultivariable linear regressionLower PAQ scoresBaseline characteristicsClinical characteristicsPAD symptomsTreatment satisfactionArterial diseaseProspective studyFemale sex
2016
Health Status Outcomes in Patients With Acute Myocardial Infarction After Rehospitalization
Shore S, Smolderen KG, Kennedy KF, Jones PG, Arnold SV, Cohen DJ, Stolker JM, Zhao Z, Wang TY, Ho PM, Spertus JA. Health Status Outcomes in Patients With Acute Myocardial Infarction After Rehospitalization. Circulation Cardiovascular Quality And Outcomes 2016, 9: 777-784. PMID: 27780850, PMCID: PMC5794496, DOI: 10.1161/circoutcomes.116.002883.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina, UnstableFemaleHealth StatusHealth Status IndicatorsHumansLinear ModelsLogistic ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionMyocardial RevascularizationPatient ReadmissionPredictive Value of TestsPropensity ScoreProspective StudiesQuality of LifeRegistriesRisk FactorsSurveys and QuestionnairesTime FactorsUnited StatesConceptsAcute myocardial infarctionComposite end pointUnplanned revascularizationUnstable anginaMyocardial infarctionHealth statusEuroQol-5D visual analogue scaleVisual analog scale scoreEnd pointUnplanned coronary revascularizationPropensity-matched cohortAnalog scale scoreSeattle Angina QuestionnaireVisual analog scaleHealth status outcomesWorse health statusAngina QuestionnaireCoronary revascularizationRehospitalization ratesAnalog scaleMean ageSuch readmissionsQuestionnaire domainsClinical trialsRehospitalization
2014
Peripheral arterial disease, gender, and depression in the Heart and Soul Study
Grenon SM, Cohen BE, Smolderen K, Vittinghoff E, Whooley MA, Hiramoto J. Peripheral arterial disease, gender, and depression in the Heart and Soul Study. Journal Of Vascular Surgery 2014, 60: 396-403. PMID: 24661811, PMCID: PMC4199228, DOI: 10.1016/j.jvs.2014.02.013.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseRisk factorsArterial diseaseDevelopment of PADStable coronary artery diseaseGender-specific risk factorsNontraditional risk factorsProspective cohort studyWorse lipid profileHistory of smokingTraditional risk factorsCoronary artery diseaseStrongest independent factorRole of depressionLogistic regression modelsSoul StudyCohort studyInflammatory biomarkersArtery diseaseDiabetes mellitusElevated fibrinogenSimilar prevalenceLipid profileHigh prevalenceIndependent factors
2012
Self-reported symptoms on questionnaires and anatomic lesions on duplex ultrasound examinations in patients with peripheral arterial disease
van Zitteren M, Vriens PW, Heyligers JM, Burger DH, Nooren MJ, de Fijter WM, Denollet J, Smolderen KG. Self-reported symptoms on questionnaires and anatomic lesions on duplex ultrasound examinations in patients with peripheral arterial disease. Journal Of Vascular Surgery 2012, 55: 1025-1034.e2. PMID: 22244858, DOI: 10.1016/j.jvs.2011.10.115.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsCross-Sectional StudiesFemaleFollow-Up StudiesHumansIntermittent ClaudicationLogistic ModelsLower ExtremityMaleMultivariate AnalysisOdds RatioPain MeasurementPeripheral Arterial DiseaseRisk FactorsSelf ReportSeverity of Illness IndexSurveys and QuestionnairesUltrasonography, Doppler, DuplexConceptsPeripheral arterial diseaseCardiovascular risk factorsDuplex ultrasound examinationDistal lesionsProximal lesionsLesion locationLeg symptomsPatient characteristicsSelf-reported symptomsArterial diseaseRisk factorsUltrasound examinationLower extremity peripheral arterial diseaseVascular surgery outpatient clinicMultivariable logistic regression analysisExertional leg symptomsNew-onset symptomsCardiovascular risk profileSurgery outpatient clinicMain outcome measuresCross-sectional studyFurther diagnostic imagingLogistic regression analysisTailor-made managementPAD subgroups
2010
Younger women with symptomatic peripheral arterial disease are at increased risk of depressive symptoms
Smolderen KG, Spertus JA, Vriens PW, Kranendonk S, Nooren M, Denollet J. Younger women with symptomatic peripheral arterial disease are at increased risk of depressive symptoms. Journal Of Vascular Surgery 2010, 52: 637-644. PMID: 20576397, DOI: 10.1016/j.jvs.2010.04.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overAnkle Brachial IndexDepressionFemaleHealth Status DisparitiesHumansIncidenceLogistic ModelsMaleMiddle AgedNetherlandsOdds RatioPeripheral Vascular DiseasesProspective StudiesPsychiatric Status Rating ScalesRegistriesRisk AssessmentRisk FactorsSex FactorsTime FactorsConceptsPeripheral arterial diseaseSignificant depressive symptomsDepressive symptomsGender-age groupsYoung womenArterial diseaseSymptomatic peripheral arterial diseaseEpidemiological Studies Depression ScaleFourfold greater oddsVascular outpatient clinicAnkle-brachial indexPatients' depressive symptomsTime of diagnosisLogistic regression modelsImportant comorbidityPAD diagnosisPAD patientsClinical factorsDepression screeningOutpatient clinicCardiovascular diseaseDepression riskDepression ScaleAdditional adjustmentGreater odds
2009
Impact of peripheral arterial disease on health status: A comparison with chronic heart failure
Smolderen KG, Pelle AJ, Kupper N, Mols F, Denollet J. Impact of peripheral arterial disease on health status: A comparison with chronic heart failure. Journal Of Vascular Surgery 2009, 50: 1391-1398. PMID: 19958988, DOI: 10.1016/j.jvs.2009.07.109.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAmbulatory Care FacilitiesChronic DiseaseCost of IllnessCross-Sectional StudiesEducational StatusFemaleHeart DiseasesHeart FailureHumansLogistic ModelsMaleMarital StatusMental HealthMiddle AgedNetherlandsOdds RatioPeripheral Vascular DiseasesPropensity ScoreRisk AssessmentRisk FactorsSickness Impact ProfileConceptsPeripheral arterial diseaseChronic heart failurePhysical health statusMental health statusCHF patientsHealth statusPAD patientsCardiac historyDiabetes mellitusHeart failureArterial diseaseMedical recordsMedical conditionsImpact of PADLow ankle-brachial indexPatients' physical health statusYounger ageWorse physical health statusCross-sectional observational studyMental health status scoresComorbid diabetes mellitusAnkle-brachial indexClinical risk factorsHealth status scoresShort Form-12Lower-leg symptoms in peripheral arterial disease are associated with anxiety, depression, and anhedonia
Smolderen KG, Hoeks SE, Pedersen SS, van Domburg RT, de Liefde II, Poldermans D. Lower-leg symptoms in peripheral arterial disease are associated with anxiety, depression, and anhedonia. Vascular Medicine 2009, 14: 297-304. PMID: 19808714, DOI: 10.1177/1358863x09104658.Peer-Reviewed Original ResearchConceptsAtypical leg symptomsPeripheral arterial diseaseExertional leg symptomsAnkle-brachial indexLeg symptomsIntermittent claudicationDepressive symptomsPAD patientsClinical factorsArterial diseaseAnkle-brachial index screeningSan Diego Claudication QuestionnaireClassic intermittent claudicationConsecutive PAD patientsLower leg symptomsDiverse clinical manifestationsErasmus Medical CenterMood statesSub-threshold symptomsCardiovascular historyMedication useTwofold riskClinical manifestationsPoor prognosisHospital AnxietyType D Personality and Mortality in Peripheral Arterial Disease: A Pilot Study
Aquarius AE, Smolderen KG, Hamming JF, De Vries J, Vriens PW, Denollet J. Type D Personality and Mortality in Peripheral Arterial Disease: A Pilot Study. JAMA Surgery 2009, 144: 728-733. PMID: 19687376, DOI: 10.1001/archsurg.2009.75.Peer-Reviewed Original ResearchConceptsPeripheral arterial diseaseType D personalityCause mortalityD personalityIndependent predictorsRenal diseaseArterial diseaseSymptomatic peripheral arterial diseasePilot studyAnkle-brachial indexHigh-risk patientsTraditional risk factorsPatients' medical filesMultivariable logistic regressionRisk of deathVascular surgery departmentType D ScaleClinical predictorsDiabetes mellitusPulmonary diseasePilot followMedical filesSurgery departmentRisk factorsTeaching hospital
2007
Personality, psychological stress, and self-reported influenza symptomatology
Smolderen K, Vingerhoets A, Croon MA, Denollet J. Personality, psychological stress, and self-reported influenza symptomatology. BMC Public Health 2007, 7: 339. PMID: 18036207, PMCID: PMC2241613, DOI: 10.1186/1471-2458-7-339.Peer-Reviewed Original Research