2024
Long‐Term Mortality Predictors Using a Machine‐Learning Approach in Patients With Chronic Limb‐Threatening Ischemia After Peripheral Vascular Intervention
Callegari S, Romain G, Cleman J, Scierka L, Jacque F, Smolderen K, Mena‐Hurtado C. Long‐Term Mortality Predictors Using a Machine‐Learning Approach in Patients With Chronic Limb‐Threatening Ischemia After Peripheral Vascular Intervention. Journal Of The American Heart Association 2024, 13: e034477. PMID: 38761075, PMCID: PMC11179837, DOI: 10.1161/jaha.124.034477.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaPeripheral vascular interventionsHealth careLimb-threatening ischemiaMortality predictorsLong-term mortality riskMultidimensional risk factorsBody mass indexLong-term mortality predictorsImprove individualized careVascular interventionsIndividualized careAssisted careBiopsychosocial modelMortality riskCareMass indexRisk factorsMedical comorbiditiesRisk profileInterventionMortality rateChronic kidney diseaseMortalityPredictive variablesComparison of mortality and amputation after lower extremity bypass versus peripheral vascular intervention in patients with chronic limb-threatening ischemia and comorbid chronic kidney disease
Cleman J, Sierra J, Romain G, Capuano B, Scierka L, Callegari S, Jacque F, Peri-Okonny P, Nagpal S, Smolderen K, Mena-Hurtado C. Comparison of mortality and amputation after lower extremity bypass versus peripheral vascular intervention in patients with chronic limb-threatening ischemia and comorbid chronic kidney disease. Journal Of Vascular Surgery 2024, 80: 480-489.e5. PMID: 38608966, DOI: 10.1016/j.jvs.2024.04.016.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaAll-cause mortalityLower extremity bypassPeripheral vascular interventionsComorbid chronic kidney diseaseLimb-threatening ischemiaComparison of mortalityPreference-sensitive treatment decisionsCox proportional hazards modelsRisk of deathInteraction termsProportional hazards modelLower-extremity bypassChronic kidney diseaseFine-Gray modelMortality riskVascular interventionsAmputationHazards modelOutcome dataFine-GrayAssociated with worse outcomesHigh riskKidney diseasePropensity scoreASSOCIATION BETWEEN CHRONIC PAIN DISORDERS IN CHRONIC LIMB THREATENING ISCHEMIA AND 30-DAY, 90-DAY AMPUTATION RISK FOLLOWING PERIPHERAL VASCULAR INTERVENTIONS
Nandigam M, Romain G, Callegari S, Cuppen S, Mares A, Hurtado C, Smolderen K. ASSOCIATION BETWEEN CHRONIC PAIN DISORDERS IN CHRONIC LIMB THREATENING ISCHEMIA AND 30-DAY, 90-DAY AMPUTATION RISK FOLLOWING PERIPHERAL VASCULAR INTERVENTIONS. Journal Of The American College Of Cardiology 2024, 83: 2307. DOI: 10.1016/s0735-1097(24)04297-9.Peer-Reviewed Original ResearchINSTITUTIONAL AND OPERATOR VARIABILITY OF IMAGING SURVEILLANCE WITHIN ONE YEAR FOLLOWING PERIPHERAL VASCULAR INTERVENTIONS FOR CHRONIC LIMB-THREATENING ISCHEMIA
Knight D, Romain G, Cleman J, Peri-Okonny P, Callegari S, Jacque F, Smolderen K, Hurtado C. INSTITUTIONAL AND OPERATOR VARIABILITY OF IMAGING SURVEILLANCE WITHIN ONE YEAR FOLLOWING PERIPHERAL VASCULAR INTERVENTIONS FOR CHRONIC LIMB-THREATENING ISCHEMIA. Journal Of The American College Of Cardiology 2024, 83: 960. DOI: 10.1016/s0735-1097(24)02950-4.Peer-Reviewed Original ResearchEvaluation of short-term mortality in patients with Medicare undergoing endovascular interventions for chronic limb-threatening ischemia
Cleman J, Romain G, Callegari S, Scierka L, Jacque F, Smolderen K, Mena-Hurtado C. Evaluation of short-term mortality in patients with Medicare undergoing endovascular interventions for chronic limb-threatening ischemia. Vascular Medicine 2024, 29: 172-181. PMID: 38334045, DOI: 10.1177/1358863x231224335.Peer-Reviewed Original ResearchChronic limb-threatening ischemiaPeripheral vascular interventionsAssisted careLimb-threatening ischemiaCongestive heart failureFunctional status variablesCrude mortality ratePredictive variablesMortality rateStatus variablesRandom survival forest modelShort-term mortalityStage 5 chronic kidney diseaseQuality InitiativeRandom survival forestTreatment conversionMedical comorbiditiesShort-term outcomesHarrell's C-indexVascular Quality InitiativeCareDementiaInterventionMortalityRisk stratification
2023
Comparison of lower extremity bypass and peripheral vascular intervention for chronic limb-threatening ischemia in the Medicare-linked Vascular Quality Initiative
Cleman J, Romain G, Grubman S, Guzman R, Smolderen K, Mena-Hurtado C. Comparison of lower extremity bypass and peripheral vascular intervention for chronic limb-threatening ischemia in the Medicare-linked Vascular Quality Initiative. Journal Of Vascular Surgery 2023, 78: 745-753.e6. PMID: 37207790, PMCID: PMC10964324, DOI: 10.1016/j.jvs.2023.05.015.Peer-Reviewed Original ResearchConceptsChronic limb-threatening ischemiaLower extremity bypassPeripheral vascular interventionsVascular Quality InitiativeLimb-threatening ischemiaCause mortalityRisk of deathExtremity bypassVascular interventionsQuality InitiativeCox proportional hazards regressionKaplan-Meier survival curvesProportional hazards regressionOverall mean ageLogistic regression modelsComparative effectiveness researchKnee poplitealMedicare registryInfrapopliteal arteriesHazards regressionMean ageThirty-dayHispanic ethnicityOutcome dataTreatment groups
2022
Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide
Harris KM, Mena-Hurtado C, Burg MM, Vriens PW, Heyligers J, Smolderen KG. Association of depression and anxiety disorders with outcomes after revascularization in chronic limb-threatening ischemia hospitalizations nationwide. Journal Of Vascular Surgery 2022, 77: 480-489. PMID: 36115521, DOI: 10.1016/j.jvs.2022.09.008.Peer-Reviewed Original ResearchConceptsLength of stayChronic limb-threatening ischemiaAnxiety disorder diagnosisAssociation of depressionRevascularization cohortMajor amputationDisorder diagnosisSurgical revascularizationEndovascular revascularizationHigher oddsLonger median LOSMedian LOSLonger LOSAnxiety disordersDocumentation of depressionPeripheral artery diseaseLimb-threatening ischemiaRisk of amputationNational Inpatient SamplePatients' sociodemographic dataHigher median costArtery diseaseIllness severityPsychiatric comorbidityComorbid depressionRisk profiles, access to care, and outcomes in Hispanics hospitalized for lower extremity peripheral artery disease
Luna P, Harris K, Castro-Dominguez Y, Algara M, Severiche-Mena C, Smolderen KG, Mena-Hurtado C. Risk profiles, access to care, and outcomes in Hispanics hospitalized for lower extremity peripheral artery disease. Journal Of Vascular Surgery 2022, 77: 216-224.e15. PMID: 36037965, DOI: 10.1016/j.jvs.2022.08.021.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseLower extremity peripheral artery diseaseNon-Hispanic whitesEmergency departmentPAD careArtery diseaseRisk factorsSevere peripheral artery diseaseChronic limb-threatening ischemiaRisk profileNational Inpatient Sample dataCardiovascular risk factorsLimb-threatening ischemiaPatients' sociodemographic characteristicsWorse clinical outcomesMultivariable logistic regressionAssociation of ethnicityLength of stayHealth care consumptionHealth care coveragePAD hospitalizationsPrior amputationEndovascular revascularizationED admissionRenal failure
2021
Patient-Reported Outcome Measures in Symptomatic, Non–Limb-Threatening Peripheral Artery Disease: A State-of-the-Art Review
Rymer JA, Narcisse D, Cosiano M, Tanaka J, McDermott MM, Treat-Jacobson DJ, Conte MS, Tuttle B, Patel MR, Smolderen KG. Patient-Reported Outcome Measures in Symptomatic, Non–Limb-Threatening Peripheral Artery Disease: A State-of-the-Art Review. Circulation Cardiovascular Interventions 2021, 15: e011320. PMID: 34937395, DOI: 10.1161/circinterventions.121.011320.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresPeripheral artery diseaseDisease-specific patient-reported outcome measureSymptomatic peripheral artery diseaseArtery diseaseOutcome measuresSelection of PROMsDisease-specific Peripheral Artery QuestionnairePeripheral Artery QuestionnaireLimb-threatening ischemiaValidation of PROMsVascular QualityImpairment QuestionnaireSF-36Life QuestionnaireInclusion criteriaCurrent evidenceEffects of diseaseHealth outcomesEuropean QualityClinical goalsLiterature searchPatientsDiseasePsychometric validation