2023
Lower extremity symptoms and ankle–brachial index screening as predictors of cardiovascular outcomes in Black adults
Lee M, Smolderen K, Ionescu C, Hillegass W, Romain G, Mena-Hurtado C. Lower extremity symptoms and ankle–brachial index screening as predictors of cardiovascular outcomes in Black adults. Vascular Medicine 2023, 28: 197-204. PMID: 37293738, DOI: 10.1177/1358863x231151729.Peer-Reviewed Original ResearchConceptsPeripheral artery diseaseAbnormal ABILower extremity symptomsNormal ABILeg symptomsHigh riskBlack adultsExtremity symptomsStepwise Cox proportional hazards modelKaplan-Meier survival curvesCox proportional hazards modelAnkle-brachial indexFramingham risk factorsJackson Heart StudyProportional hazards modelCardiovascular outcomesCause mortalityArtery diseaseAsymptomatic diseaseAdverse outcomesMean ageSymptom assessmentAsymptomatic participantsRisk factorsSymptomatic participants
2022
A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment
Rome D, Sales A, Leeds R, Usseglio J, Cornelius T, Monk C, Smolderen KG, Moise N. A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment. Current Atherosclerosis Reports 2022, 24: 709-720. PMID: 35751731, PMCID: PMC9398966, DOI: 10.1007/s11883-022-01048-0.Peer-Reviewed Original ResearchConceptsCoronary heart diseaseCardiovascular diseaseMechanism of actionHeart diseaseNarrative reviewManagement of depressionPrevalence of depressionRecent FindingsWomenCardiovascular outcomesAutonomic factorsDepression treatmentComorbid depressionTreatment inertiaGreater prevalenceTherapeutic targetPrevalenceStrong associationWomenDepressionDiseaseGreater mortalityTreatment effectsAssociationMenTreatment
2018
Depression and long-term prognostic outcomes following peripheral endovascular interventions in the VA Healthcare System
Smolderen KG, Plomondon ME, Armstrong EJ, Hess E, Waldo S, Tsai TT, Maddox TM. Depression and long-term prognostic outcomes following peripheral endovascular interventions in the VA Healthcare System. Vascular Medicine 2018, 23: 454-460. PMID: 29801427, DOI: 10.1177/1358863x18770275.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedChi-Square DistributionComorbidityDepressionEndovascular ProceduresFemaleHumansHypertensionKaplan-Meier EstimateMaleMiddle AgedMyocardial InfarctionPeripheral Arterial DiseaseProportional Hazards ModelsRetrospective StudiesRisk FactorsStrokeTime FactorsTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsNon-fatal cardiovascular eventsPeripheral vascular interventionsCardiovascular eventsDiagnosis of depressionHazard ratioMedical recordsAge-adjusted hazard ratioLong-term prognostic outcomesNon-fatal cardiovascular outcomesPeripheral endovascular interventionsLong-term outcomesPatients' medical recordsVA healthcare systemVeterans Affairs centersCause deathCardiovascular outcomesConsecutive patientsAdditional covariatesEndovascular interventionRecent diagnosisPrognostic outcomesDepressed patientsDisease outcomeVascular interventionsHigh risk
2014
Gender Differences in Health Status and Adverse Outcomes Among Patients With Peripheral Arterial Disease
Dreyer RP, van Zitteren M, Beltrame JF, Fitridge R, Denollet J, Vriens PW, Spertus JA, Smolderen KG. Gender Differences in Health Status and Adverse Outcomes Among Patients With Peripheral Arterial Disease. Journal Of The American Heart Association 2014, 4: e000863. PMID: 25537275, PMCID: PMC4330046, DOI: 10.1161/jaha.114.000863.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmbulatory Care FacilitiesCohort StudiesFemaleFollow-Up StudiesHealth StatusHealth Status IndicatorsHumansMaleMental HealthMiddle AgedMultivariate AnalysisNetherlandsPeripheral Arterial DiseasePhysical FitnessProportional Hazards ModelsRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsSurvival AnalysisTime FactorsConceptsPeripheral artery diseaseMajor adverse eventsPAD diagnosisAdverse eventsHealth statusMCS scoresLong-term major adverse eventsSelf-reported health statusBaseline clinical dataPeripheral arterial diseaseShort Form-12Time of presentationSubsequent adverse eventsPoor socio-economic statusMental health statusCardiovascular outcomesClinical characteristicsArtery diseaseVascular clinicArterial diseaseForm-12Independent determinantsInitial diagnosisAdverse outcomesPCS scores
2011
Accuracy and Prognostic Value of American Heart Association–Recommended Depression Screening in Patients With Coronary Heart Disease
Elderon L, Smolderen KG, Na B, Whooley MA. Accuracy and Prognostic Value of American Heart Association–Recommended Depression Screening in Patients With Coronary Heart Disease. Circulation Cardiovascular Quality And Outcomes 2011, 4: 533-540. PMID: 21862720, DOI: 10.1161/circoutcomes.110.960302.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmerican Heart AssociationComorbidityCoronary DiseaseDepressionDepressive Disorder, MajorDiagnostic Tests, RoutineFemaleFollow-Up StudiesHumansMaleMiddle AgedMyocardial InfarctionPredictive Value of TestsPrognosisRiskSensitivity and SpecificitySurveys and QuestionnairesSurvival AnalysisUnited StatesConceptsCoronary heart diseaseAmerican Heart AssociationStable coronary heart diseasePatient Health QuestionnaireMajor depressive disorderHeart diseaseCardiovascular eventsPrognostic valueHeart AssociationDepressive disorderHealth QuestionnaireHigh-density lipoprotein levelsDepression screening protocolSubsequent cardiovascular eventsAdverse cardiovascular outcomesBody mass indexGold standard interviewCardiovascular outcomesIdentifies patientsHeart failureScreening methodLipoprotein levelsMass indexDepression screeningMyocardial infarction