2024
Maternal Adverse Childhood Experiences and Biological Aging During Pregnancy and in Newborns
Dye C, Alschuler D, Wu H, Duarte C, Monk C, Belsky D, Lee S, O’Donnell K, Baccarelli A, Scorza P. Maternal Adverse Childhood Experiences and Biological Aging During Pregnancy and in Newborns. JAMA Network Open 2024, 7: e2427063. PMID: 39120899, PMCID: PMC11316241, DOI: 10.1001/jamanetworkopen.2024.27063.Peer-Reviewed Original ResearchConceptsMaternal adverse childhood experiencesAdverse childhood experiencesEdinburgh Postnatal Depression ScaleAccessible Resource for Integrated Epigenomics StudiesEpigenetic age accelerationGestational age accelerationAssociated with epigenetic agingAvon Longitudinal Study of ParentsLongitudinal Study of ParentsPostnatal Depression ScalePrimary outcomeChildhood experiencesAvon Longitudinal StudyEpigenetic ageStudy of ParentsAge accelerationHigher ACE scoresCross-sectional studyEpigenetic clocksMother-offspring dyadsDepression ScaleHealth districtMother-child dyadsDNA methylation–based epigenetic clocksInvestigate depression
2010
Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy
King NM, Chambers J, O’Donnell K, Jayaweera SR, Williamson C, Glover VA. Anxiety, depression and saliva cortisol in women with a medical disorder during pregnancy. Archives Of Women's Mental Health 2010, 13: 339-345. PMID: 20101421, DOI: 10.1007/s00737-009-0139-5.Peer-Reviewed Original ResearchConceptsMedical disordersSaliva cortisolDiurnal saliva samplesAdverse pregnancy outcomesHigher EPDS scoresSubgroup of womenExtra psychological supportSelf-rating questionnaireVs. 35.2Antenatal womenHyperemesis gravidarumPregnancy outcomesEPDS scoresPregnant womenVs. 5.9Neurodevelopmental problemsCortisol levelsHealth professionalsPregnancySaliva samplesDisorder groupElevated levelsPsychological supportWomenDisorders