2011
The impact of prostate edema on cell survival and tumor control after permanent interstitial brachytherapy for early stage prostate cancers
Chen Z, Roberts K, Decker R, Pathare P, Rockwell S, Nath R. The impact of prostate edema on cell survival and tumor control after permanent interstitial brachytherapy for early stage prostate cancers. Physics In Medicine And Biology 2011, 56: 4895-4912. PMID: 21772076, PMCID: PMC3154133, DOI: 10.1088/0031-9155/56/15/016.Peer-Reviewed Original ResearchConceptsPermanent interstitial brachytherapyProstate edemaProstate cancerEffects of edemaTumor control probabilityImpact of edemaInterstitial brachytherapyCell survivalEarly-stage prostate cancerControl probabilityStage prostate cancerCurrent clinical practiceProstate cancer cellsTumor cell proliferationInterstitial brachytherapy treatmentSublethal damage repairDose variationTumor cell survivalTumor characteristicsTumor controlClinical impactEdemaEdema evolutionClinical practiceProstate gland
2007
TH‐E‐M100E‐07: The Impact of Procedure‐Induced Edema On Cell Survival and Tumor Control Probability in Permanent Prostate Brachytherapy Using 131Cs Radioactive Source
Chen Z, Deng J, Roberts K, Nath R. TH‐E‐M100E‐07: The Impact of Procedure‐Induced Edema On Cell Survival and Tumor Control Probability in Permanent Prostate Brachytherapy Using 131Cs Radioactive Source. Medical Physics 2007, 34: 2655-2655. DOI: 10.1118/1.2761777.Peer-Reviewed Original ResearchTumor control probabilityBiologically effective doseControl probabilityPermanent prostate brachytherapyRadioactive sourcesConcept of biologically effective doseProstate brachytherapyProstate edemaEdema magnitudeProtracted dose deliveryPotential doubling timeRepair half-timeCell survivalDose deliveryEffectiveness of cell killingCell killingTumor potential doubling timeSurviving fraction of cancer cellsEdema-induced increaseInitial tumor burdenFraction of cancer cellsRadiation-induced cell killingHalf-lifeDoubling timeTumor burden