2010
The Distribution and Most Recent Common Ancestor of the 17q21 Inversion in Humans
Donnelly MP, Paschou P, Grigorenko E, Gurwitz D, Mehdi SQ, Kajuna SL, Barta C, Kungulilo S, Karoma NJ, Lu RB, Zhukova OV, Kim JJ, Comas D, Siniscalco M, New M, Li P, Li H, Manolopoulos VG, Speed WC, Rajeevan H, Pakstis AJ, Kidd JR, Kidd KK. The Distribution and Most Recent Common Ancestor of the 17q21 Inversion in Humans. American Journal Of Human Genetics 2010, 86: 161-171. PMID: 20116045, PMCID: PMC2820164, DOI: 10.1016/j.ajhg.2010.01.007.Peer-Reviewed Original Research
2001
A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans
Barbulescu M, Turner G, Su M, Kim R, Jensen-Seaman M, Deinard A, Kidd K, Lenz J. A HERV-K provirus in chimpanzees, bonobos and gorillas, but not humans. Current Biology 2001, 11: 779-783. PMID: 11378389, DOI: 10.1016/s0960-9822(01)00227-5.Peer-Reviewed Original ResearchConceptsTransposable genetic elementsDNA sequencing studiesHERV-K provirusesUnique insertion sitesAfrican great apesChimpanzee genomeEvolutionary separationPhylogenetic relationshipsOrthologous positionsCommon ancestorHuman genomeModern speciesPreintegration siteGenetic elementsSequencing studiesGenomeEndogenous retrovirusesHuman evolutionGreat apesLineagesGorillasSpeciesHERVInsertion siteChimpanzees
2000
Evolution of exon 1 of the dopamine D4 receptor (DRD4) gene in primates
Seaman M, Chang F, Deinard A, Quiñones A, Kidd K. Evolution of exon 1 of the dopamine D4 receptor (DRD4) gene in primates. Journal Of Experimental Zoology 2000, 288: 32-38. PMID: 10750051, DOI: 10.1002/(sici)1097-010x(20000415)288:1<32::aid-jez4>3.0.co;2-g.Peer-Reviewed Original ResearchConceptsHigh conservationOld World monkeysWorld monkeysTandem repeatsPrimate speciesExon 1Amino acid sequenceReceptor geneGreat apesRelaxed selectionEvolutionary historyD4 receptor geneHomologous exonsInterspecific differencesNew World monkeysDopamine D4 receptor geneAcid sequenceSelective pressureFirst exonTandem duplicationExonsExon 3SpeciesGenesRepeats
1999
Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles
Palmatier M, Kang A, Kidd K. Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles. Biological Psychiatry 1999, 46: 557-567. PMID: 10459407, DOI: 10.1016/s0006-3223(99)00098-0.Peer-Reviewed Original ResearchConceptsRestriction site polymorphismsSingle nucleotide polymorphismsAllele frequenciesDifferent population frequenciesControl allele frequenciesEnzyme activity levelsAncestral alleleCandidate genesPopulation-based association studyAssociation studiesSite polymorphismFirst global surveyNucleotide polymorphismsAllelesEnzyme activityPopulation frequencyPolymorphismDifferent populationsCOMT enzyme activityActivity alleleLow-activity alleleGenesProteinGlobal variationPopulation
1998
A Global Haplotype Analysis of the Myotonic Dystrophy Locus: Implications for the Evolution of Modern Humans and for the Origin of Myotonic Dystrophy Mutations
Tishkoff S, Goldman A, Calafell F, Speed W, Deinard A, Bonne-Tamir B, Kidd J, Pakstis A, Jenkins T, Kidd K. A Global Haplotype Analysis of the Myotonic Dystrophy Locus: Implications for the Evolution of Modern Humans and for the Origin of Myotonic Dystrophy Mutations. American Journal Of Human Genetics 1998, 62: 1389-1402. PMID: 9585589, PMCID: PMC1377140, DOI: 10.1086/301861.Peer-Reviewed Original ResearchConceptsNon-African populationsHaplotype diversityMyotonic dystrophy locusRecent African origin modelLinkage disequilibriumMyotonic dystrophy mutationModern human evolutionModern humansGlobal haplotype analysisMutation eventsStrong linkage disequilibriumNonhuman primate speciesPrimate speciesHuman evolutionHuman populationShared pattern
1997
Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion
Liao D, Pavelitz T, Kidd J, Kidd K, Weiner A. Concerted evolution of the tandemly repeated genes encoding human U2 snRNA (the RNU2 locus) involves rapid intrachromosomal homogenization and rare interchromosomal gene conversion. The EMBO Journal 1997, 16: 588-598. PMID: 9034341, PMCID: PMC1169662, DOI: 10.1093/emboj/16.3.588.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceChromosomesCloning, MolecularDNA, SatelliteElectrophoresis, Agar GelEvolution, MolecularGenetic MarkersHaplotypesHumansLinkage DisequilibriumMolecular Sequence DataPedigreePolymorphism, GeneticPolymorphism, Restriction Fragment LengthPrimatesRecombination, GeneticRepetitive Sequences, Nucleic AcidRNA, Small NuclearSequence AnalysisConceptsU2 tandem arrayTandem arraysConcerted evolutionIntrachromosomal homogenizationU2 snRNAInterchromosomal gene conversionHuman U2 snRNARepeat unitsGenetic exchangeU2 genesGene conversionChromosome lineagesIndependent assortmentFlanking markersDiverse panelGenesMicrosatellite polymorphismSnRNACT alleleSacISacI polymorphismPolymorphismAllelesChromatid exchangesPrimary driving force
1996
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
Tishkoff S, Dietzsch E, Speed W, Pakstis A, Kidd J, Cheung K, Bonné-Tamir B, Santachiara-Benerecetti A, Moral P, Krings M, Pääbo S, Watson E, Risch N, Jenkins T, Kidd K. Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins. Science 1996, 271: 1380-1387. PMID: 8596909, DOI: 10.1126/science.271.5254.1380.Peer-Reviewed Original Research
1990
Monomorphism in humans and sequence differences among higher primates for a sequence tagged site (STS) in homeo box cluster 2 as assayed by denaturing gradient electrophoresis
Ruano G, Gray M, Miki T, Ferguson-Smith A, Ruddle F, Kidd K. Monomorphism in humans and sequence differences among higher primates for a sequence tagged site (STS) in homeo box cluster 2 as assayed by denaturing gradient electrophoresis. Nucleic Acids Research 1990, 18: 1314-1314. PMID: 1969622, PMCID: PMC330476, DOI: 10.1093/nar/18.5.1314.Peer-Reviewed Original Research