2008
Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
Lee M, Mukherjee N, Pakstis A, Khaliq S, Mohyuddin A, Mehdi S, Speed W, Kidd J, Kidd K. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene. The Pharmacogenomics Journal 2008, 8: 349-356. PMID: 18663376, PMCID: PMC2782390, DOI: 10.1038/tpj.2008.9.Peer-Reviewed Original ResearchConceptsGenetic variationGene expressionAssociation studiesFamily of enzymesDifferent human populationsHaplotype variationHuman population samplesMajor geographical regionsTandem repeatsPolymorphism haplotypesGenesMultiple populationsHaplotypesSusceptibility mutationsGlobal patternsHuman populationAdditional polymorphismsHaplotype frequenciesCentral roleDifferent populationsDiverse patternsEndogenous compoundsDisequilibriumLD dataPolymorphism
1996
Conserved regulatory element involved in the early onset of Hoxb6 gene expression
Becker D, Jiang Z, Knödler P, Deinard A, Eid R, Kidd K, Shashikant C, Ruddle F, Schughart K. Conserved regulatory element involved in the early onset of Hoxb6 gene expression. Developmental Dynamics 1996, 205: 73-81. PMID: 8770553, DOI: 10.1002/(sici)1097-0177(199601)205:1<73::aid-aja7>3.0.co;2-2.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceConserved SequenceDNADNA PrimersEmbryonic and Fetal DevelopmentEnhancer Elements, GeneticGene Expression Regulation, DevelopmentalGenes, HomeoboxGenes, RegulatorGenes, ReporterHomeodomain ProteinsHumansIn Situ HybridizationMesodermMiceMice, TransgenicMolecular Sequence DataSequence Homology, Nucleic AcidConceptsGene expressionPosterior lateral plate mesodermConserved regulatory elementsLateral plate mesodermReporter gene analysisSimilar enhancer activityHuman DNA sequencesBp DNA fragmentMammalian embryosMouse developmentPlate mesodermRegulatory elementsDNA sequencesEnhancer activityExpression patternsDNA fragmentsGene analysisEnhancerTransgenic miceExpressionInitial activationEarly stagesMesodermEmbryosTransgene