2018
Response to Letter to the Editor concerning manuscript, “Blood pressure variability predicts adverse events and cardiovascular outcomes in sprint”
Mezue K, Goyal A, Pressman G, Matthew R, Horrow J, Rangaswami J. Response to Letter to the Editor concerning manuscript, “Blood pressure variability predicts adverse events and cardiovascular outcomes in sprint”. Journal Of Clinical Hypertension 2018, 20: 1646-1647. PMID: 30328256, PMCID: PMC8030952, DOI: 10.1111/jch.13400.Peer-Reviewed Original ResearchBlood pressure variability predicts adverse events and cardiovascular outcomes in SPRINT
Mezue K, Goyal A, Pressman G, Matthew R, Horrow J, Rangaswami J. Blood pressure variability predicts adverse events and cardiovascular outcomes in SPRINT. Journal Of Clinical Hypertension 2018, 20: 1247-1252. PMID: 29984884, PMCID: PMC8031192, DOI: 10.1111/jch.13346.Peer-Reviewed Original ResearchConceptsAdverse eventsDiastolic BPCardiovascular outcomesDiastolic BP-CVSystolic BPAntihypertensive therapyTreatment armsRate of treatment-related adverse eventsPrimary outcomeTreatment-related adverse eventsBlood pressureEffects of antihypertensive therapyCox proportional hazards regressionAcute kidney injuryCompare treatment armsPredictors of outcomeVisit-to-visitStudent's t-testTarget systolic BPProportional hazards regressionBlood pressure variabilityLevels of BPSPRINT dataVisit-to-visit DBP variabilityIndependent predictors
2017
Clinical hypertension: Blood pressure variability
Malik E, Abdulhadi B, Mezue K, Lerma E, Rangaswami J. Clinical hypertension: Blood pressure variability. Disease-a-Month 2017, 64: 5-13. PMID: 28939280, DOI: 10.1016/j.disamonth.2017.08.003.Peer-Reviewed Original ResearchBlood Pressure Variability Predicts Adverse Events and Cardiovascular Outcomes in Chronic Kidney Disease: A Post-Hoc Analysis of the SPRINT Trial
Mezue K, Goyal A, Pressman G, Horrow J, Rangaswami J. Blood Pressure Variability Predicts Adverse Events and Cardiovascular Outcomes in Chronic Kidney Disease: A Post-Hoc Analysis of the SPRINT Trial. American Journal Of Hypertension 2017, 31: 48-52. PMID: 28985328, DOI: 10.1093/ajh/hpx128.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseAcute kidney injuryDiastolic blood pressureDBP CVVisit-to-visitCardiovascular outcomesBlood pressure variabilityAdverse eventsPrimary outcomeKidney diseaseBlood pressureAssociated with adverse cardiovascular outcomesVisit-to-visit blood pressure variabilityCox proportional hazards regressionTarget systolic blood pressureAdverse cardiovascular outcomesPressure variabilityProportional hazards regressionSystolic blood pressurePredicting adverse eventsPost hoc analysisVisit-to-visit DBP variabilityAntihypertensive therapyIndependent predictorsKidney injuryVisit‐to‐visit systolic blood pressure variability predicts treatment‐related adverse event of hyponatremia in SPRINT
Goyal A, Mezue K, Rangaswami J. Visit‐to‐visit systolic blood pressure variability predicts treatment‐related adverse event of hyponatremia in SPRINT. Cardiovascular Therapeutics 2017, 35 PMID: 28544636, DOI: 10.1111/1755-5922.12274.Peer-Reviewed Original ResearchConceptsVisit-to-visit systolic blood pressure variabilitySystolic blood pressureSystolic blood pressure variabilityTarget blood pressureBlood pressureBlood pressure variabilitySPRINT trialAdverse eventsSystolic blood pressure <Occurrence of hyponatremiaCox proportional hazards regressionRisk of hyponatremiaBlood pressure <Coefficient of variation of systolic blood pressureProportional hazards regressionStandard treatment groupCardiovascular risk factorsPressure variabilityOverall cohortTreatment armsTreatment subgroupsHazards regressionInclusion criteriaCoefficient of variationHyponatremiaOutcomes of Intensive Blood Pressure Lowering in Older Hypertensive Patients Should AKI Be Watched?
Naranjo M, Mezue K, Rangaswami J. Outcomes of Intensive Blood Pressure Lowering in Older Hypertensive Patients Should AKI Be Watched? Journal Of The American College Of Cardiology 2017, 70: 119-120. PMID: 28662802, DOI: 10.1016/j.jacc.2017.02.078.Peer-Reviewed Original ResearchSystolic Blood Pressure Variability Is Obstructive Sleep Apnea a Bigger Factor at Play?
Mezue K, Krishnamoorthy P, Rangaswami J. Systolic Blood Pressure Variability Is Obstructive Sleep Apnea a Bigger Factor at Play? Journal Of The American College Of Cardiology 2017, 69: 908. PMID: 28209234, DOI: 10.1016/j.jacc.2016.10.081.Peer-Reviewed Original Research
2016
Letter by Mezue et al Regarding Article, “Effect of Intensive Versus Usual Blood Pressure Control on Kidney Function Among Individuals With Prior Lacunar Stroke
Mezue K, Puri R, Rangaswami J. Letter by Mezue et al Regarding Article, “Effect of Intensive Versus Usual Blood Pressure Control on Kidney Function Among Individuals With Prior Lacunar Stroke. Circulation 2016, 134: e24-e25. PMID: 27462060, DOI: 10.1161/circulationaha.116.022381.Peer-Reviewed Original ResearchNocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage.
Mezue K, Isiguzo G, Madu C, Nwuruku G, Rangaswami J, Baugh D, Madu E. Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage. Ethnicity & Disease 2016, 26: 279-84. PMID: 27440966, PMCID: PMC4948793, DOI: 10.18865/ed.26.3.279.Peer-Reviewed Original ResearchConceptsCardiac target organ damageTarget organ damageNon-dippersBlood pressure profileNocturnal blood pressureOrgan damageBlood pressureBlack normotensivesNon-dipping of blood pressureMass indexCardiovascular riskLeft atrial volume indexLeft ventricular mass indexCardiovascular end-organ damageIncreased relative wall thicknessAtrial volume indexAmbulatory blood pressure patternsNon-dipper groupVentricular mass indexNocturnal non-dippingNon-dipping profileNon-dipping patternPredictor of cardiovascular riskEnd-organ damageNon-dipping blood pressure profile