Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity
Mezue K, Osborne M, Abbasi T, Zureigat H, Abohashem S, Gharios C, Akuffo E, Cardeiro A, Pitman R, Shin L, Jaffer F, Rosovsky R, Tawakol A. Moderate alcohol intake associates with a decreased risk of venous thrombosis: mediation through decreased stress-associated brain activity. European Heart Journal 2021, 42: ehab724.2046. DOI: 10.1093/eurheartj/ehab724.2046.Peer-Reviewed Original ResearchModerate alcohol intakeDeep venous thrombosisAlcohol intakeNeural activityEffects of alcoholEffects of moderate alcoholVenous thrombosisDecreased riskNeural effectsMedian follow-up periodDeep venous thrombosis riskBrain activityMediation analysisRisk of deep venous thrombosisIncidence of deep venous thrombosisRisk of venous thrombosisDecreased risk of venous thrombosisAdult participantsEmission tomography imagingCox regression analysisFollow-up periodNeural pathwaysNeurobiological activityFollow-up outcome informationModerate alcoholAnxiety and depression associate with heightened risk of deep venous thrombosis: mediation through neural pathways
Mezue K, Osborne M, Abohashem S, Zureigat H, Abbasi T, Gharios C, Cardeiro A, Akuffo E, Pitman R, Shin L, Jaffer F, Rosovsky R, Tawakol A. Anxiety and depression associate with heightened risk of deep venous thrombosis: mediation through neural pathways. European Heart Journal 2021, 42: ehab724.2045. DOI: 10.1093/eurheartj/ehab724.2045.Peer-Reviewed Original ResearchAnxiety disordersInternational Classification of DiseasesRisk of deep venous thrombosisDeep venous thrombosisNeural activityNeural pathwaysFollow-up periodMass General Brigham BiobankIncreased riskClassification of DiseasesBiobank enrollmentVenous thrombosisIncreased risk of DVTCancer historyIncreased risk of deep venous thrombosisHealth informationMediation analysisDeep venous thrombosis riskInternational ClassificationMedian follow-up periodPotential confoundersAnxietyLower extremity deep venous thrombosisExtremity deep venous thrombosisDepression