Novel Oral Anticoagulants in Atrial Fibrillation: Update on Apixaban
Mezue K, Obiagwu C, John J, Sharma A, Yang F, Shani J. Novel Oral Anticoagulants in Atrial Fibrillation: Update on Apixaban. Current Cardiology Reviews 2017, 13: 41-46. PMID: 27450450, PMCID: PMC5324317, DOI: 10.2174/1573403x12666160720092024.Peer-Reviewed Original ResearchConceptsFood and Drug AdministrationAtrial fibrillationReversal agentsClinical trialsNon-valvular atrial fibrillationSignificant mitral stenosisNovel oral anticoagulantsUS Food and Drug AdministrationOnset of actionPrimary safety outcomeClinical trial dataPrevention of strokeRate of strokeInhibitors of factor XaProsthetic heart valvesClinical bleedingApixaban useSystemic embolismOral anticoagulantsINR monitoringMitral stenosisDose variabilityNOACsApixabanCardiac arrhythmias