2023
Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy
Kaman K, Dhodapkar M, Shabanova V, McCollum S, Factor J, Leeds S. Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy. Annals Of Allergy Asthma & Immunology 2023, 130: 657-663. PMID: 36738780, DOI: 10.1016/j.anai.2023.01.028.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyOral immunotherapyNon-white racePeanut allergyAnxiety scoresOlder cohortProspective cross-sectional cohort studyCross-sectional cohort studyHigher mean anxiety scoresMean anxiety scoreDiagnosable anxietyCohort studyMale patientsPediatric patientsFemale patientsFood allergySimilar patientsHigh prevalenceHigher scoresLife measuresLow prevalencePatientsSeparation anxiety scoresElectronic survey questionnaireAllergyParent-reported penicillin allergies in children: A qualitative study.
Carter EJ, Kaman K, Baron K, Miller M, Krol DM, Harpalani D, Aseltine RH, Pagoto S. Parent-reported penicillin allergies in children: A qualitative study. Am J Infect Control 2023, 51: 56-61. PMID: 35537563, DOI: 10.1016/j.ajic.2022.04.008.Peer-Reviewed Original Research
2022
A practical focus on sesame allergy and a brief review of other seed allergies
Kaman, K. Factor, J. A practical focus on sesame allergy and a brief review of other seed aller-gies. Journal of Food Allergy. July 2022.Peer-Reviewed Original ResearchPeripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic Esophagitis.
Shin, J. Kaman, K. Anthonypillai, J. Soffer, G. Kang, I. (2022). Peripheral Blood Cell Counts Predict Distinct Endoscopic Phenotypes In Eosinophilic Esophagitis. Journal of Allergy and Clinical Immunology. February 2022.Peer-Reviewed Original Research
2021
The immunologic response to severe acute respiratory syndrome coronavirus 2.
Le NK, Kaman K, Martin HC, Mullur J, Stenehjem KK, Coomar L, Bahar B, Dutta M, Izurieta R, Brooks JP. The immunologic response to severe acute respiratory syndrome coronavirus 2. Allergy Asthma Proc 2021, 42: 495-505. PMID: 34871157, DOI: 10.2500/aap.2021.42.210077.Peer-Reviewed Original ResearchCytokine profiles in severe SARS-CoV-2 infection requiring extracorporeal membrane oxygenation support
Kaman K, Azmy V, Chichra A, Britto-Leon C, Price C. Cytokine profiles in severe SARS-CoV-2 infection requiring extracorporeal membrane oxygenation support. Respiratory Medicine Case Reports 2021, 33: 101376. PMID: 33680800, PMCID: PMC7925237, DOI: 10.1016/j.rmcr.2021.101376.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenation supportMembrane oxygenation supportVV-ECMOOxygenation supportCytokine stormVeno-venous extracorporeal membrane oxygenation supportSevere SARS-CoV-2 infectionSARS-CoV-2 infectionVV-ECMO supportRefractory respiratory failureProspective cohort studyCohort of patientsInterleukin-2 receptorCytokine elevationHyperinflammatory stateECMO supportRespiratory failureCohort studyCytokine profileClinical courseInterleukin-10COVID19 patientsUnderlying pathophysiologyInterleukin-6Inflammatory responseNovel Compound Heterozygous Mutations in ZAP70 Leading to a SCID Phenotype with Normal Downstream In vitro Signaling.
Kaman K, Abrams M, Dobbs K, Notarangelo LD, Delmonte OM, Palterer B, Pai SY, Johnston A. Novel Compound Heterozygous Mutations in ZAP70 Leading to a SCID Phenotype with Normal Downstream In vitro Signaling. J Clin Immunol 2021, 41: 470-472. PMID: 33184721, DOI: 10.1007/s10875-020-00913-4.Peer-Reviewed Case Reports and Technical NotesA retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients
Ringer M, Azmy V, Kaman K, Tang D, Cheung H, Azar MM, Price C, Malinis M. A retrospective matched cohort single‐center study evaluating outcomes of COVID‐19 and the impact of immunomodulation on COVID‐19‐related cytokine release syndrome in solid organ transplant recipients. Transplant Infectious Disease 2021, 23: e13556. PMID: 33378571, PMCID: PMC7883059, DOI: 10.1111/tid.13556.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedCase-Control StudiesCohort StudiesComorbidityCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeFemaleGlucocorticoidsGraft RejectionHeart TransplantationHospitalizationHumansImmunologic FactorsImmunosuppressive AgentsInterleukin-10Interleukin-6Kidney TransplantationLiver TransplantationMaleMiddle AgedReceptors, Interleukin-2Retrospective StudiesSARS-CoV-2Severity of Illness IndexTreatment OutcomeYoung AdultConceptsCytokine release syndromeBody mass indexNon-SOT patientsSOT groupSOT patientsRelease syndromeInterleukin-6COVID-19-related cytokine release syndromeSoluble interleukin-2 receptor levelsControl groupInterleukin-2 receptor levelsSolid organ transplant patientsSolid organ transplant recipientsImpact of immunomodulationInterleukin-10 levelsOrgan transplant recipientsOrgan transplant patientsCritical care needsMulti-center studyCoronavirus disease 2019COVID-19Interleukin levelsIndex hospitalizationTransplant patientsTransplant recipientsCytokine Profiles Before and After Immune Modulation in Hospitalized Patients with COVID-19
Azmy V, Kaman K, Tang D, Zhao H, Dela Cruz C, Topal JE, Malinis M, Price CC. Cytokine Profiles Before and After Immune Modulation in Hospitalized Patients with COVID-19. Journal Of Clinical Immunology 2021, 41: 738-747. PMID: 33459964, PMCID: PMC7812117, DOI: 10.1007/s10875-020-00949-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedBiomarkersCOVID-19COVID-19 Drug TreatmentCytokine Release SyndromeCytokinesDrug Therapy, CombinationFeasibility StudiesFemaleGlucocorticoidsHospitalizationHumansImmunologic FactorsMaleMiddle AgedRetrospective StudiesSARS-CoV-2Severity of Illness IndexTreatment OutcomeYoung AdultConceptsIL-10 levelsIL-6IL-10Disease severityCytokine profileD-dimerTreatment algorithmCritical SARS-CoV-2 infectionCOVID-19SARS-CoV-2 infectionAdministration of tocilizumabAdmission IL-6Maximum oxygen requirementsTocilizumab-treated patientsElevated IL-6Immune-modulating therapyCritical COVID-19Retrospective chart reviewTertiary care centerIL-6 levelsMean IL-6IL-6 inhibitionAdministration of glucocorticoidsRole of cytokinesCytokine elevationThe Impact of Food Matrices on Egg Allergenicity.
Kaman K, Leeds S. The Impact of Food Matrices on Egg Allergenicity. Journal of Food Allergy. August 2021.Peer-Reviewed Case Reports and Technical Notes
2020
Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report.
Soffer G, Kaman K, Li XM. Successful Management of Eosinophilic Esophagitis Using Traditional Chinese Medicine: A Case Report. The Yale Journal Of Biology And Medicine 2020, 93: 685-688. PMID: 33380930, PMCID: PMC7757072.Peer-Reviewed Original ResearchConceptsTraditional Chinese medicineEosinophilic esophagitisChinese medicineQuality of lifeComplete remissionTopical steroidsFood eliminationTh2 cytokinesCase reportLabel useEoESuccessful managementEsophagitisTreatmentFurther modalitiesMedicineRemissionPatientsPathophysiologyCytokinesSteroidsPrevalenceTocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes
Price CC, Altice FL, Shyr Y, Koff A, Pischel L, Goshua G, Azar MM, Mcmanus D, Chen SC, Gleeson SE, Britto CJ, Azmy V, Kaman K, Gaston DC, Davis M, Burrello T, Harris Z, Villanueva MS, Aoun-Barakat L, Kang I, Seropian S, Chupp G, Bucala R, Kaminski N, Lee AI, LoRusso PM, Topal JE, Dela Cruz C, Malinis M. Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes. CHEST Journal 2020, 158: 1397-1408. PMID: 32553536, PMCID: PMC7831876, DOI: 10.1016/j.chest.2020.06.006.Peer-Reviewed Original ResearchConceptsCytokine release syndromeTocilizumab-treated patientsSevere diseaseRelease syndromeTocilizumab treatmentInflammatory biomarkersNonsevere diseaseSoluble IL-2 receptor levelsHigh-sensitivity C-reactive proteinIL-2 receptor levelsConsecutive COVID-19 patientsIL-6 receptor antagonistMechanical ventilation outcomesC-reactive proteinCOVID-19 patientsHigher admission levelsRace/ethnicityMV daysVentilation outcomesAdverse eventsChart reviewClinical responseMedian ageWhite patientsClinical outcomesRepurposing antimicrobial stewardship tools in the electronic medical record for the management of COVID-19 patients
Davis MW, McManus D, Koff A, Jaszczur GR, Malinis M, Dela Cruz C, Britto CJ, Price C, Azmy V, Kaman K, Gaston D, Early K, DeWitt M, Song JS, Ortiz C, Juthani-Mehta M, Topal JE. Repurposing antimicrobial stewardship tools in the electronic medical record for the management of COVID-19 patients. Infection Control And Hospital Epidemiology 2020, 41: 1335-1337. PMID: 32507113, PMCID: PMC7308631, DOI: 10.1017/ice.2020.281.Peer-Reviewed Original Research