Nicotine and Nicotine Abstinence Do Not Interfere with GABAA Receptor Neuroadaptations During Alcohol Abstinence
Hillmer AT, Kloczynski T, Sandiego CM, Pittman B, Anderson JM, Labaree D, Gao H, Huang Y, Deluliis G, O'Malley SS, Carson RE, Cosgrove KP. Nicotine and Nicotine Abstinence Do Not Interfere with GABAA Receptor Neuroadaptations During Alcohol Abstinence. Alcohol Clinical And Experimental Research 2016, 40: 698-705. PMID: 26971694, PMCID: PMC4983773, DOI: 10.1111/acer.12997.Peer-Reviewed Original ResearchConceptsGABAA receptor availabilityPositron emission tomographyAlcohol abstinenceAlcohol withdrawalNicotine abstinenceReceptor availabilityTobacco smokingNonhuman primatesContinued nicotine useNicotine replacement therapyWeeks of abstinenceSelf-administer alcoholAdolescent male rhesus macaquesDays of abstinenceSignificant group effectMale rhesus macaquesNicotine cessationNicotine exposureReplacement therapyNicotine useAlcohol dependenceEmission tomographyDrug abstinenceSmokingNicotine