Specific Triggering of the Fas Signal Transduction Pathway in Normal Human Keratinocytes*
Freiberg R, Spencer D, Choate K, Peng P, Schreiber S, Crabtree G, Khavari P. Specific Triggering of the Fas Signal Transduction Pathway in Normal Human Keratinocytes*. Journal Of Biological Chemistry 1996, 271: 31666-31669. PMID: 8940187, DOI: 10.1074/jbc.271.49.31666.Peer-Reviewed Original ResearchConceptsFas signal transduction pathwaySignal transduction pathwaysCytoplasmic domainTransduction pathwaysReceptor cytoplasmic domainFas signal transductionSignal transductionConstitutive promoterPlasma membraneGenotoxic injuryHuman keratinocytesFK1012Membrane receptorsCell typesPoint mutationsFA effectsViability of keratinocytesPhorbol esterSpecific triggeringGrowth stimuliFKBPBinding stepCellular changesNormal human keratinocytesProtein