Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevisoocyte
Tanemoto M, Vanoye C, Dong K, Welch R, Abe T, Hebert S, Xu J. Rat homolog of sulfonylurea receptor 2B determines glibenclamide sensitivity of ROMK2 in Xenopus laevisoocyte. American Journal Of Physiology. Renal Physiology 2000, 278: f659-f666. PMID: 10751228, DOI: 10.1152/ajprenal.2000.278.4.f659.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsATP-Binding Cassette TransportersFemaleGlyburideKidneyMolecular Sequence DataOocytesPotassium ChannelsPotassium Channels, Inwardly RectifyingProtein IsoformsRatsReceptors, DrugSequence Homology, Amino AcidSulfonylurea ReceptorsTranscription, GeneticXenopus laevisConceptsThick ascending limbAscending limbCortical thick ascending limbRT-PCRMedullary thick ascending limbGlibenclamide sensitivityGlibenclamide effectsRat homologIntrarenal distributionSulfonylurea receptor 2BProximal tubulesDistal distributionSulfonylurea receptorRenal ATPSkeletal muscleRat tissuesXenopus laevis oocytesROMK proteinGlibenclamideRat kidney cDNA librarySUR2BTubulesROMKLimbLaevis oocytes