Therapeutic efficacy of SJA6017, a calpain inhibitor, in rat spinal cord injury
Akdemir O, Uçankale M, Karaoğlan A, Barut Ş, Sağmanligil A, Bilguvar K, Çirakoğlu B, Şahan E, Çolak A. Therapeutic efficacy of SJA6017, a calpain inhibitor, in rat spinal cord injury. Journal Of Clinical Neuroscience 2008, 15: 1130-1136. PMID: 18656362, DOI: 10.1016/j.jocn.2007.08.011.Peer-Reviewed Original ResearchConceptsSpinal cord injuryGroup 3 ratsCord injuryRat spinal cord injury modelGrading scaleRat spinal cord injurySpinal cord injury modelApoptotic cell deathSpinal cord traumaGroup 2 ratsFeasible therapeutic strategySpinal cord tissueWistar albino ratsNecrosis 24 hCell deathTarlov scoreModerate traumaCord traumaNeuroprotective effectsFunctional recoveryFunctional outcomeLimb functionNeurological performanceWidespread edemaInjury model