Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type: longitudinal observation of radiographic findings in a child heterozygous for a KIF22 mutation
Tüysüz B, Yılmaz S, Erener-Ercan T, Bilguvar K, Günel M. Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type: longitudinal observation of radiographic findings in a child heterozygous for a KIF22 mutation. Pediatric Radiology 2014, 45: 771-776. PMID: 25256152, DOI: 10.1007/s00247-014-3159-x.Peer-Reviewed Original ResearchConceptsYears of ageShort statureRadiologic findingsJoint laxityMidface hypoplasiaLeptodactylic typeSevere genu valgumTypical radiologic findingsPostnatal short statureDe novo p.Whole-exome sequencingInitial radiographsSevere involvementRadiographic findingsHip dislocationGenu valgumKnee subluxationLigamentous laxitySmall epiphysisRare disorderDistal metaphysisProximal phalanxRadiologic hallmarksNovo p.First examination