2023
Nodal tumor volume as a prognostic factor for oral squamous cell carcinoma—a systematic review
Bernasconi M, Bilic A, Kauke-Navarro M, Safi A. Nodal tumor volume as a prognostic factor for oral squamous cell carcinoma—a systematic review. Frontiers In Oral Health 2023, 4: 1229931. PMID: 37654649, PMCID: PMC10467257, DOI: 10.3389/froh.2023.1229931.Peer-Reviewed Original ResearchOral squamous cell carcinomaNodal tumor volumeSquamous cell carcinomaPrognostic factorsPrognostic significanceCell carcinomaTumor volumeSystematic reviewAccurate nodal stagingLymph node metastasisNodal disease burdenNovel prognostic factorPoor survival outcomesPoor survival rateTraditional staging methodsNode metastasisSurvival outcomesNodal stagingDisease burdenInclusion criteriaPrognostic assessmentOSCC managementElectronic databasesSurvival rateMajority of studies
2018
Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma?
Safi AF, Kauke M, Jung H, Timmer M, Borggrefe J, Persigehl T, Nickenig HJ, Zinser M, Maintz D, Kreppel M, Zöller J. Does volumetric measurement of cervical lymph nodes serve as an imaging biomarker for locoregional recurrence of oral squamous cell carcinoma? Journal Of Cranio-Maxillofacial Surgery 2018, 46: 1013-1018. PMID: 29709330, DOI: 10.1016/j.jcms.2018.04.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersCarcinoma, Squamous CellChemoradiotherapyFemaleHumansLymph NodesLymphatic MetastasisMaleMicrosurgeryMiddle AgedMouth NeoplasmsMultivariate AnalysisNeckNeck DissectionNeoadjuvant TherapyNeoplasm Recurrence, LocalPrognosisRetrospective StudiesRisk FactorsTomography, X-Ray ComputedConceptsOral squamous cell carcinomaLymph node volumeSquamous cell carcinomaLocoregional recurrenceN classificationCell carcinomaNode volumeInclusion criteriaComputed tomographyTreatment-naive oral squamous cell carcinomaIpsilateral lymph node metastasisBetter risk stratification toolsComprehensive neck dissectionPathological N classificationCervical lymph nodesNegative resection marginsRetrospective chart reviewRisk stratification toolLymph node metastasisPreoperative computed tomographyVolumetric measurementsT4b classificationUnresectable diseaseLocoregional failureNeoadjuvant chemoradiotherapy