The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1
Choe H, Farzan M, Konkel M, Martin K, Sun Y, Marcon L, Cayabyab M, Berman M, Dorf M, Gerard N, Gerard C, Sodroski J. The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1. Journal Of Virology 1998, 72: 6113-6118. PMID: 9621075, PMCID: PMC110417, DOI: 10.1128/jvi.72.7.6113-6118.1998.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1Immunodeficiency virus type 1Virus type 1T cell line tropicType 1Peripheral blood mononuclear cellsHIV-1 infectionHIV-1 isolatesBlood mononuclear cellsHIV-1 coreceptorsChemokine receptor CCR5Such coreceptorsMononuclear cellsAsymptomatic stageReceptor APJReceptor CCR5HIV-1Infected individualsCoreceptorAPJTarget cellsInfectionReceptorsViral evolutionSIVmac316