Coordinating Regulation of Gene Expression in Cardiovascular Disease: Interactions between Chromatin Modifiers and Transcription Factors
Bauer AJ, Martin KA. Coordinating Regulation of Gene Expression in Cardiovascular Disease: Interactions between Chromatin Modifiers and Transcription Factors. Frontiers In Cardiovascular Medicine 2017, 4: 19. PMID: 28428957, PMCID: PMC5382160, DOI: 10.3389/fcvm.2017.00019.Peer-Reviewed Original ResearchChromatin modifiersTranscription factorsGene expressionTranscriptional controlChromatin-modifying proteinsTranscription factor recruitmentDysregulated gene expressionNumerous cell typesChromatin structureFactor recruitmentHistone methylationGene accessibilityTranscriptional interactionsDNA methylationEpigenetic modifiersRegulatory regionsHistone acetylationVascular smooth muscle cellsCell typesSmooth muscle cellsMuscle cellsMethylationNovel therapeuticsExpressionDisease pathogenesis