2018
Cesarean Scar Pregnancy, Incidence, and Recurrence
Grechukhina O, Deshmukh U, Fan L, Kohari K, Abdel-Razeq S, Bahtiyar MO, Sfakianaki AK. Cesarean Scar Pregnancy, Incidence, and Recurrence. Obstetrics And Gynecology 2018, 132: 1285-1295. PMID: 30303911, DOI: 10.1097/aog.0000000000002940.Peer-Reviewed Original ResearchMeSH KeywordsAbortifacient Agents, NonsteroidalAdultCesarean SectionCicatrixCombined Modality TherapyCurettageFemaleHumansHysteroscopyMethotrexatePotassium ChloridePregnancyPregnancy RatePregnancy, EctopicRecurrenceTertiary Care CentersUterine Artery EmbolizationUterine Balloon TamponadeWatchful WaitingYoung AdultConceptsCesarean scar pregnancyScar pregnancySubsequent pregnancy outcomeLocal methotrexatePregnancy outcomesTreatment modalitiesRecurrent cesarean scar pregnancyBilateral uterine artery embolizationElectronic medical record reviewYale-New Haven HospitalSubsequent spontaneous conceptionViable intrauterine pregnancyPrior cesarean deliveryMedical record reviewTime of diagnosisUterine artery embolizationPotassium chloride injectionFetal cardiac activityProducts of conceptionIntrauterine pregnancyPregnancy characteristicsSystemic methotrexateExpectant managementMethotrexate therapyArtery embolization
2016
Outcome after implementation of a modern management strategy for intrahepatic cholestasis of pregnancy
Kohari KS, Carroll R, Capogna S, Ditchik A, Fox NS, Ferrara LA. Outcome after implementation of a modern management strategy for intrahepatic cholestasis of pregnancy. The Journal Of Maternal-Fetal & Neonatal Medicine 2016, 30: 1342-1346. PMID: 27418248, DOI: 10.1080/14767058.2016.1212833.Peer-Reviewed Original ResearchConceptsNeonatal outcomesIntrahepatic cholestasisBile acidsContinuous fetal heart rate monitoringModern management strategiesGreater maternal ageRetrospective cohort studyFetal heart rate monitoringCesarean delivery rateTotal bile acidsNew management protocolNew cohortNICU admissionGestational diabetesSingleton gestationsCohort studyPatient demographicsPregnancy outcomesInpatient admissionsMaternal ageHeart rate monitoringStillbirth rateWeeksCholestasisOutcomesMitochondrial gene expression profiles are associated with intrahepatic cholestasis of pregnancy
Mella MT, Kohari K, Jones R, Peña J, Ferrara L, Stone J, Lambertini L. Mitochondrial gene expression profiles are associated with intrahepatic cholestasis of pregnancy. Placenta 2016, 45: 16-23. PMID: 27577705, DOI: 10.1016/j.placenta.2016.07.002.Peer-Reviewed Original ResearchConceptsOxidative stress statusIntrahepatic cholestasisHepatic bile acid accumulationHigher maternal serum levelsMaternal serum levelsSpontaneous preterm birthNon-pregnant stateBile acid levelsBile acid concentrationsBile acid accumulationStress statusPathophysiology of ICPOxidative stress ratePreterm birthClinical courseFetal demiseSerum levelsFetal effectsPregnant womenHigh oxidative stressReal-time PCRLong-term effectsMitochondrial activityPlacenta samplesBile acids