The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway
Tan D, Cai Y, Wang J, Zhang J, Menon S, Chou HT, Ferro-Novick S, Reinisch KM, Walz T. The EM structure of the TRAPPIII complex leads to the identification of a requirement for COPII vesicles on the macroautophagy pathway. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 19432-19437. PMID: 24218626, PMCID: PMC3845172, DOI: 10.1073/pnas.1316356110.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAutophagyChlorocebus aethiopsChromatography, GelCloning, MolecularCOP-Coated VesiclesCOS CellsElectroporationEscherichia coliImage Processing, Computer-AssistedMicroscopy, ElectronMicroscopy, FluorescenceModels, MolecularProtein ConformationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVesicular Transport ProteinsConceptsPhagophore assembly siteCOPII vesiclesAssembly sitesRab GTPase Ypt1Electron microscopy structureTargeting of ERTRAPPIII complexFusion machineryMicroscopy structureCOPII coatMacroautophagy pathwayExchange factorSubunit associatesMembrane sourceEM structuresAcceptor compartmentTRAPPIIITRAPPIVesiclesMacroautophagyTrs85COPIISec23Ypt1Mammals