2024
Assessment of online information on robotic cardiac and thoracic surgery
Hameed I, Amabile A, Candelario K, Khan S, Li E, Fereydooni S, Almeida M, Latif N, Ahmed A, Dhanasopon A, Krane M, Blasberg J, Geirsson A. Assessment of online information on robotic cardiac and thoracic surgery. Journal Of Robotic Surgery 2024, 18: 41. PMID: 38231324, DOI: 10.1007/s11701-023-01794-6.Peer-Reviewed Original ResearchConceptsThoracic surgeryAmount of contentConfidence intervalsOnline informationReadability of online resourcesOnline health informationSystematic online searchPerioperative informationCardiothoracic surgeonsOnline health resourcesAcademic websitesSurgeryPatientsReadability of websitesThoracicMultivariate regressionHigher accuracyWebsite accuracyPatient useHealth informationReadabilityWebsitesAccuracyAssociated with higher accuracyIndependent panel
2022
Thoracic CT follow-up after non-small-cell lung cancer resection
Woodard G, Boffa D, Blasberg J. Thoracic CT follow-up after non-small-cell lung cancer resection. The Lancet Oncology 2022, 23: e484. PMID: 36328013, DOI: 10.1016/s1470-2045(22)00618-0.Commentaries, Editorials and LettersThe Society of Thoracic Surgeons General Thoracic Surgery Database: 2022 Update on Outcomes and Research
Servais E, Blasberg J, Brown L, Towe C, Seder C, Onaitis M, Block M, David E. The Society of Thoracic Surgeons General Thoracic Surgery Database: 2022 Update on Outcomes and Research. The Annals Of Thoracic Surgery 2022, 115: 43-49. PMID: 36404445, DOI: 10.1016/j.athoracsur.2022.10.025.Peer-Reviewed Original ResearchImmunotherapy After Chemotherapy and Radiation for Clinical Stage III Lung Cancer
Pichert MD, Canavan ME, Maduka RC, Li AX, Ermer T, Zhan PL, Kaminski M, Udelsman BV, Blasberg JD, Park HS, Goldberg SB, Boffa DJ. Immunotherapy After Chemotherapy and Radiation for Clinical Stage III Lung Cancer. JAMA Network Open 2022, 5: e2224478. PMID: 35925606, PMCID: PMC9353596, DOI: 10.1001/jamanetworkopen.2022.24478.Peer-Reviewed Original ResearchConceptsStage III non-small cell lung cancerNon-small cell lung cancerClinical stage III non-small cell lung cancerUnresectable stage III non-small cell lung cancerPropensity-matched sampleGeneral US populationSurvival advantageCohort studyLung cancerMultivariable Cox proportional hazards modelsUS populationStage III lung cancerMedian age 66 yearsCox proportional hazards modelNational Cancer DatabaseEfficacy of immunotherapyAge 66 yearsProtocol rangesCell lung cancerClinical trial populationsProportional hazards modelTerms of ageImmunotherapy initiationImmunotherapy recipientsImmunotherapy useSurgical Management of Pneumothorax and Pleural Space Disease
Dhanasopon AP, Blasberg JD, Mase VJ. Surgical Management of Pneumothorax and Pleural Space Disease. Surgical Clinics Of North America 2022, 102: 413-427. PMID: 35671764, DOI: 10.1016/j.suc.2022.03.001.Peer-Reviewed Original ResearchMicrowave Ablation versus Stereotactic Body Radiotherapy for Stage I Non–Small Cell Lung Cancer: A Cost-Effectiveness Analysis
Wu X, Uhlig J, Blasberg JD, Gettinger SN, Suh RD, Solomon SB, Kim HS. Microwave Ablation versus Stereotactic Body Radiotherapy for Stage I Non–Small Cell Lung Cancer: A Cost-Effectiveness Analysis. Journal Of Vascular And Interventional Radiology 2022, 33: 964-971.e2. PMID: 35490932, DOI: 10.1016/j.jvir.2022.04.019.Peer-Reviewed Original Research
2021
Evolution of the N Descriptor Lymph Node Number vs Lymph Node Location
Blasberg JD, Li A. Evolution of the N Descriptor Lymph Node Number vs Lymph Node Location. CHEST Journal 2021, 159: 2159-2160. PMID: 34099129, DOI: 10.1016/j.chest.2021.01.065.Peer-Reviewed Original ResearchHumansTongue DiseasesEffectiveness of Thermal Ablation and Stereotactic Radiotherapy Based on Stage I Lung Cancer Histology
Uhlig J, Mehta S, Case MD, Dhanasopon A, Blasberg J, Homer RJ, Solomon SB, Kim HS. Effectiveness of Thermal Ablation and Stereotactic Radiotherapy Based on Stage I Lung Cancer Histology. Journal Of Vascular And Interventional Radiology 2021, 32: 1022-1028.e4. PMID: 33811997, DOI: 10.1016/j.jvir.2021.02.025.Peer-Reviewed Original ResearchConceptsStereotactic body radiotherapyStage I lung cancerI lung cancerOverall survivalHistological subtypesNeuroendocrine tumorsCell carcinomaLung cancerThermal ablationPropensity scoreMost histological subtypesNational Cancer DatabaseSignificant OS differenceAmerican Joint CommitteeLarge cell carcinomaSmall cell carcinomaHigher overall survivalSquamous cell carcinomaLung cancer histologyLung cancer variesSmall neuroendocrine tumorsMore comorbiditiesTA patientsCancer variesInitial treatmentAdjuvant Chemotherapy for T4 Non-Small Cell Lung Cancer with Additional Ipsilateral Lung Nodules
Li AX, Flores K, Canavan ME, Boffa DJ, Blasberg JD. Adjuvant Chemotherapy for T4 Non-Small Cell Lung Cancer with Additional Ipsilateral Lung Nodules. The Annals Of Thoracic Surgery 2021, 113: 421-428. PMID: 33684345, DOI: 10.1016/j.athoracsur.2021.02.042.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerDifferent ipsilateral lobeCell lung cancerAdditional tumor nodulesT4 non-small cell lung cancerAdjuvant chemotherapyIpsilateral lobeT4 diseaseTumor nodulesLung cancerT4 tumorsOverall survivalSurgical resectionIIIA non-small cell lung cancerAdjuvant multiagent chemotherapyResectable stage IINational Cancer DatabaseFurther prospective studiesLymph node metastasisMultiagent chemotherapyNode metastasisPrimary outcomeProspective studyPatient populationCancer DatabaseA Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications.
Colquhoun DA, Leis AM, Shanks AM, Mathis MR, Naik BI, Durieux ME, Kheterpal S, Pace NL, Popescu WM, Schonberger RB, Kozower BD, Walters DM, Blasberg JD, Chang AC, Aziz MF, Harukuni I, Tieu BH, Blank RS. A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications. Anesthesiology 2021, 134: 562-576. PMID: 33635945, PMCID: PMC8274370, DOI: 10.1097/aln.0000000000003729.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureOne-lung ventilationPostoperative pulmonary complicationsEnd-expiratory pressurePulmonary complicationsProtective ventilationTidal volumeThoracic surgeryMajor postoperative pulmonary complicationsVentilation regimenLung resection surgeryRetrospective observational analysisThoracic Surgeons databaseMedian tidal volumeLung resection proceduresUnmatched cohortMajor surgeryPrimary outcomeResection surgerySurgeons databaseIndependent associationResection proceduresDecreased oddsIntraoperative dataComplications
2020
A National Study of Surgically Managed Atypical Pulmonary Carcinoid Tumors
Walters SL, Canavan ME, Salazar MC, Resio BJ, Blasberg JD, Mase V, Boffa DJ. A National Study of Surgically Managed Atypical Pulmonary Carcinoid Tumors. The Annals Of Thoracic Surgery 2020, 112: 921-927. PMID: 33159862, DOI: 10.1016/j.athoracsur.2020.09.029.Peer-Reviewed Original ResearchConceptsAtypical pulmonary carcinoid tumorsPulmonary carcinoid tumorsCarcinoid tumorsCarcinoid patientsAtypical carcinoidStage IMultivariable Cox proportional hazards regressionNon-small cell lung cancerCox proportional hazards regressionAtypical carcinoid patientsTypical pulmonary carcinoidNational Cancer DatabasePredictors of survivalOptimal surgical managementAtypical carcinoid tumorCell lung cancerProportional hazards regressionKaplan-Meier survivalLong-term survivalNodal upstagingSurgical resectionMultivariable analysisSurgical managementHazards regressionLarge tumorsInvasive Staging Procedures Do Not Prevent Nodal Metastases From Being Missed in Stage I Lung Cancer
Resio BJ, Canavan M, Mase V, Dhanasopon AP, Blasberg JD, Boffa DJ. Invasive Staging Procedures Do Not Prevent Nodal Metastases From Being Missed in Stage I Lung Cancer. The Annals Of Thoracic Surgery 2020, 110: 390-397. PMID: 32283084, DOI: 10.1016/j.athoracsur.2020.03.026.Peer-Reviewed Original ResearchConceptsStage I lung cancerI lung cancerMissed nodal metastasisClinical stage I lung cancerNodal metastasisLung cancerPositron emission tomographyStaging evaluationCancer patientsEndobronchial ultrasoundInvasive nodalClinical stage I patientsEarly-stage lung cancer patientsOccult lymph node metastasisEmission tomographyThoracic Surgeons General Thoracic Surgery DatabaseInvasive staging proceduresClinical stage IStage I patientsTreatment-naive patientsGeneral Thoracic Surgery DatabaseLow-risk cohortOccult nodal metastasisLymph node metastasisLung cancer patientsSurgically Managed Signet Ring Cell Esophageal Carcinomas in the National Cancer Database
Sathe TS, Resio BJ, Hoag JR, Monsalve AF, Pathak R, Blasberg JD, Mase V, Dhanasopon A, Boffa DJ. Surgically Managed Signet Ring Cell Esophageal Carcinomas in the National Cancer Database. The Annals Of Thoracic Surgery 2020, 109: 1656-1662. PMID: 32109449, DOI: 10.1016/j.athoracsur.2020.01.021.Peer-Reviewed Original ResearchConceptsSignet ring cell adenocarcinomaNational Cancer DatabaseSRC tumorsACA patientsCancer DatabaseProportional hazards regression modelsCommon histologic variantRole of esophagectomyClinical stage IRole of surgeryHazards regression modelsHigh-grade tumorsSRC histologySRC patientsAdult patientsComplete resectionWorse prognosisCell adenocarcinomaEsophageal cancerEsophageal carcinomaHistologic variantsSuperior survivalEsophageal adenocarcinomaTreatment characteristicsClinical recommendationsRobotic Thoracic Surgery
Schwartz G, Sancheti M, Blasberg J. Robotic Thoracic Surgery. Surgical Clinics Of North America 2020, 100: 237-248. PMID: 32169178, DOI: 10.1016/j.suc.2019.12.001.Peer-Reviewed Original ResearchConceptsThoracic surgical interventionRobotic thoracic surgeryLung resectionMediastinal tumorMajor anatomic structuresSurgical managementSurgical interventionThoracic incisionMeticulous dissectionThoracic surgeryImproved outcomesPathologic conditionsRobotic approachAnatomic regionsInvasive surgeryBenefits translateAnatomic structuresSurgeryDissectionOutcomesMorbidityResectionPatientsTumorsChestUnderstanding Entrustment Decision-Making by Surgical Program Directors
Ahle SL, Gielissen K, Keene DE, Blasberg JD. Understanding Entrustment Decision-Making by Surgical Program Directors. Journal Of Surgical Research 2020, 249: 74-81. PMID: 31926399, DOI: 10.1016/j.jss.2019.12.001.Peer-Reviewed Original ResearchConceptsNetwork of facultyCognitive competenciesTrainee supervisorsSurgical program directorsTraining programTrainee performanceReflexive trustTrainee competenceCompetenceTaskClinical tasksEntrustment decisionsTraineesInductive approachTrainingCritical themesOperating roomQualitative analysisNovel themesTrustCompetenciesPurposive samplingInterviewsProgram directorsPhysical presence
2019
Digital Inference of Immune Microenvironment Reveals Low-Risk Subtype of Early Lung Adenocarcinoma
Kurbatov V, Balayev A, Saffarzadeh A, Heller DR, Boffa DJ, Blasberg JD, Lu J, Khan SA. Digital Inference of Immune Microenvironment Reveals Low-Risk Subtype of Early Lung Adenocarcinoma. The Annals Of Thoracic Surgery 2019, 109: 343-349. PMID: 31568747, DOI: 10.1016/j.athoracsur.2019.08.050.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinoma of LungAdultAgedCohort StudiesDatabases, FactualDisease-Free SurvivalFemaleHumansImmunotherapyKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedNeoplasm InvasivenessNeoplasm StagingPneumonectomyPrognosisProportional Hazards ModelsRetrospective StudiesRisk AssessmentSurvival AnalysisTumor MicroenvironmentConceptsTumor immune microenvironmentImmune microenvironmentLung adenocarcinomaOverall survivalRisk groupsMast cellsCox proportional hazard modelingEarly-stage lung adenocarcinomaLow-risk subtypesKaplan-Meier analysisPathological staging systemProportional hazard modelingImproved clinical outcomesCancer immune microenvironmentImmune cell typesEarly lung adenocarcinomaActivation stateClinical outcomesValidation cohortMacrophage contentStaging systemMultivariable modelCIBERSORT analysisPatientsClinical decisionComparison of Survival Rates After a Combination of Local Treatment and Systemic Therapy vs Systemic Therapy Alone for Treatment of Stage IV Non–Small Cell Lung Cancer
Uhlig J, Case MD, Blasberg JD, Boffa DJ, Chiang A, Gettinger SN, Kim HS. Comparison of Survival Rates After a Combination of Local Treatment and Systemic Therapy vs Systemic Therapy Alone for Treatment of Stage IV Non–Small Cell Lung Cancer. JAMA Network Open 2019, 2: e199702. PMID: 31433481, PMCID: PMC6707019, DOI: 10.1001/jamanetworkopen.2019.9702.Peer-Reviewed Original ResearchMeSH KeywordsAblation TechniquesAdolescentAdultAgedAged, 80 and overAntineoplastic AgentsCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantComparative Effectiveness ResearchDatabases, FactualFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoplasm MetastasisNeoplasm StagingPneumonectomyProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSurvival RateTreatment OutcomeYoung AdultConceptsStage IV non-small cell lung cancerNon-small cell lung cancerPrimary tumor siteSuperior overall survivalSystemic therapySurgical resectionCell lung cancerExternal beam radiotherapyOverall survivalSurvival benefitLocal treatmentTumor siteTumor characteristicsLung cancerTreatment groupsMultivariable Cox proportional hazards regression modelsOligometastatic non-small cell lung cancerStage IV squamous cell carcinomaSurvival rateCox proportional hazards regression modelProportional hazards regression modelsComparative effectiveness research studyCancer-specific factorsNational Cancer DatabaseStage IV diseaseQuality Versus Quantity
Chiu AS, Arnold BN, Hoag JR, Herrin J, Kim CH, Salazar MC, Monsalve AF, Jean RA, Blasberg JD, Detterbeck FC, Gross CP, Boffa DJ. Quality Versus Quantity. Annals Of Surgery 2019, Publish Ahead of Print: &na;. PMID: 29697446, DOI: 10.1097/sla.0000000000002762.Peer-Reviewed Original ResearchConceptsComplex cancer surgeryCancer surgerySafe hospitalComplex oncologic surgeryPotential mortality reductionNational Cancer DatabaseHigh-volume hospitalsHospital quality measuresSurgical mortalityPrimary cancerHospital rating systemsOncologic surgeryCancer DatabaseMortality reductionSurgical volumeHospital safetyPatient realignmentPatientsHospitalSurgeryMeaningful reductionPublic reportingMortalityRSMRCancerDifferential Safety Between Top-Ranked Cancer Hospitals and Their Affiliates for Complex Cancer Surgery
Hoag JR, Resio BJ, Monsalve AF, Chiu AS, Brown LB, Herrin J, Blasberg JD, Kim AW, Boffa DJ. Differential Safety Between Top-Ranked Cancer Hospitals and Their Affiliates for Complex Cancer Surgery. JAMA Network Open 2019, 2: e191912. PMID: 30977848, PMCID: PMC6481444, DOI: 10.1001/jamanetworkopen.2019.1912.Peer-Reviewed Original ResearchConceptsComplex cancer surgeryCancer surgeryCancer HospitalMedicare beneficiariesCancer NetworkRelative safetyStandardized mortality ratioComplex cancer careCross-sectional studyTop-ranked hospitalsMedicaid Services 100Hierarchical logistic regressionPerioperative mortalityAffiliated HospitalCancer careMortality ratioOdds ratioMAIN OUTCOMESurgeryHospitalReview filesDifferential safetyLogistic regressionMortalityMedicare providersThe Society of Thoracic Surgeons General Thoracic Surgery Database 2019 Update on Outcomes and Quality
Seder CW, Magee MJ, Broderick SR, Brown LM, Blasberg JD, Kozower BD, Fernandez FG, Welsh R, Gaissert HA, Burfeind W, Becker S, Raymond D. The Society of Thoracic Surgeons General Thoracic Surgery Database 2019 Update on Outcomes and Quality. The Annals Of Thoracic Surgery 2019, 107: 1302-1306. PMID: 30898564, DOI: 10.1016/j.athoracsur.2019.02.027.Peer-Reviewed Original Research