2016
Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery
Thomas DC, Arnold BN, Rosen JE, Salazar MC, Blasberg JD, Detterbeck FC, Boffa DJ, Kim AW. Defining outcomes of patients with clinical stage I small cell lung cancer upstaged at surgery. Lung Cancer 2016, 103: 75-81. PMID: 28024700, DOI: 10.1016/j.lungcan.2016.11.016.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantCombined Modality TherapyDatabases, FactualFemaleGuidelines as TopicHumansLung NeoplasmsLymphatic MetastasisMaleMiddle AgedNeoplasm StagingOutcome Assessment, Health CarePneumonectomyPostoperative PeriodRadiotherapySmall Cell Lung CarcinomaSurvival AnalysisConceptsStage I small cell lung cancerClinical stage ISmall cell lung cancerCell lung cancerAdjuvant chemotherapySurgical resectionPathologic upstagingStage IRadiation therapyNodal diseaseLung cancerPositive lymph node involvementNational Cancer DatabaseOutcomes of patientsLymph node involvementProportion of patientsCurative intentNodal upstagingSCLC patientsUpstaged patientsAdjuvant therapyNode involvementIndependent predictorsInferior survivalT descriptorRole of Adjuvant Therapy for Node-Negative Lung Cancer Invading the Chest Wall
Gao SJ, Corso CD, Blasberg JD, Detterbeck FC, Boffa DJ, Decker RH, Kim AW. Role of Adjuvant Therapy for Node-Negative Lung Cancer Invading the Chest Wall. Clinical Lung Cancer 2016, 18: 169-177.e4. PMID: 27890561, DOI: 10.1016/j.cllc.2016.08.005.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerAdjuvant chemotherapyAdjuvant chemoradiation therapyUnderwent surgeryChemoradiation therapyChest wall resectionRadiation therapyMargin statusTumor sizeLung cancerWall resectionNode-negative lung cancerNational Cancer Data BaseCox proportional hazards modelMargin-positive patientsChest wall invasionCell lung cancerLog-rank testStage IIB tumorsProportional hazards modelAdjuvant therapyAdjuvant treatmentOverall survivalMultivariable analysisIIB tumorsTiming of Surgery after Neoadjuvant Chemoradiation in Locally Advanced Non–Small Cell Lung Cancer
Gao SJ, Corso CD, Wang EH, Blasberg JD, Detterbeck FC, Boffa DJ, Decker RH, Kim AW. Timing of Surgery after Neoadjuvant Chemoradiation in Locally Advanced Non–Small Cell Lung Cancer. Journal Of Thoracic Oncology 2016, 12: 314-322. PMID: 27720827, DOI: 10.1016/j.jtho.2016.09.122.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaCarcinoma, Large CellCarcinoma, Non-Small-Cell LungCarcinoma, Squamous CellChemoradiotherapy, AdjuvantCombined Modality TherapyFemaleFollow-Up StudiesHumansLung NeoplasmsMaleMiddle AgedNeoadjuvant TherapyNeoplasm StagingPneumonectomyPrognosisRetrospective StudiesSurvival RateTime FactorsConceptsNational Cancer Data BaseNeoadjuvant chemoradiationTiming of surgeryOverall survivalAdvanced non-small cell lung cancerNon-small cell lung cancerStage IIIA-N2 NSCLCStage IIIA NSCLCKaplan-Meier methodOverall survival rateSubset of patientsCell lung cancerLog-rank testMultivariate survival analysisProportional hazards modelIIIA NSCLCN2 NSCLCNeoadjuvant therapyTrimodality therapySurgical resectionClinical stageRetrospective studyLung cancerHazards modelSurvival rate
2011
Management of Early Stage Non–Small Cell Lung Cancer in High-Risk Patients
Donington JS, Blasberg JD. Management of Early Stage Non–Small Cell Lung Cancer in High-Risk Patients. Thoracic Surgery Clinics 2011, 22: 55-65. PMID: 22108689, DOI: 10.1016/j.thorsurg.2011.08.018.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungCombined Modality TherapyHumansLung NeoplasmsNeoplasm StagingTime FactorsConceptsNon-small cell lung cancerEarly-stage non-small cell lung cancerHigh-risk patientsCell lung cancerLung cancerStage I non-small cell lung cancerStage non-small cell lung cancerPeri-procedural morbidityOperable lung cancerType of resectionRefinement of indicationsAnatomic resectionMediastinal lymphSublobar resectionOncologic efficacyTreatment optionsPreferred treatmentResectionPatientsCancerTreatmentLobectomyLymphMorbidityMortality
2010
Robotic Brachytherapy and Sublobar Resection for T1 Non-Small Cell Lung Cancer in High-Risk Patients
Blasberg JD, Belsley SJ, Schwartz GS, Evans A, Wernick I, Ashton RC, Bhora FY, Connery CP. Robotic Brachytherapy and Sublobar Resection for T1 Non-Small Cell Lung Cancer in High-Risk Patients. The Annals Of Thoracic Surgery 2010, 89: 360-367. PMID: 20103299, DOI: 10.1016/j.athoracsur.2009.09.052.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedAged, 80 and overBrachytherapyCombined Modality TherapyComorbidityDisease ProgressionFemaleFollow-Up StudiesHealth Status IndicatorsHumansImage Processing, Computer-AssistedIodine RadioisotopesLung NeoplasmsMaleMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPneumonectomyPositron-Emission TomographyPostoperative ComplicationsRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRadiotherapy, AdjuvantRoboticsTomography, X-Ray ComputedConceptsNon-small cell lung cancerHigh-risk patientsCell lung cancerPlanning target volumeSublobar resectionLung cancerPrescription doseStage IA non-small cell lung cancerTarget volumeT1 non-small cell lung cancerSublobar lung resectionPatients 5 yearsSite of recurrenceIncidence of recurrenceComputed tomography scanBrachytherapy seed placementDa Vinci systemConventional lobectomyPerioperative mortalityLocoregional recurrenceLung resectionSelect patientsLimited resectionResection marginsTumor size