2011
Onconase mediated NFKβ downregulation in malignant pleural mesothelioma
Goparaju CM, Blasberg JD, Volinia S, Palatini J, Ivanov S, Donington JS, Croce C, Carbone M, Yang H, Pass HI. Onconase mediated NFKβ downregulation in malignant pleural mesothelioma. Oncogene 2011, 30: 2767-2777. PMID: 21317924, PMCID: PMC3118086, DOI: 10.1038/onc.2010.643.Peer-Reviewed Original ResearchConceptsDownstream targetsMiRNA mimicsCell linesCell proliferationSoft agar colony formationMPM cell linesMiRNA expression patternsAgar colony formationProtein translationABC transportersExpression patternsGene expressionReverse transcription-PCRSpecific microRNAsBcl-xLCertain miRNAsMiRNA expressionOnconaseFunctional assaysClosure assayFunctional implicationsMatrigel invasionColony formationCell apoptosisNuclear factor kappa B
2010
Functional Heterogeneity of Osteopontin Isoforms in Non-small Cell Lung Cancer
Goparaju CM, Pass HI, Blasberg JD, Hirsch N, Donington JS. Functional Heterogeneity of Osteopontin Isoforms in Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2010, 5: 1516-1523. PMID: 20689445, PMCID: PMC3122268, DOI: 10.1097/jto.0b013e3181eba6bd.Peer-Reviewed Original ResearchApoptosisBiomarkers, TumorBlotting, WesternCarcinoma, Non-Small-Cell LungCell AdhesionCell Line, TumorCell MovementCell ProliferationColony-Forming Units AssayEpithelial-Mesenchymal TransitionGene Expression ProfilingHumansLung NeoplasmsOligonucleotide Array Sequence AnalysisOsteopontinProtein IsoformsReverse Transcriptase Polymerase Chain ReactionRNA, MessengerWound Healing