2021
Adjuvant Chemotherapy for T4 Non-Small Cell Lung Cancer with Additional Ipsilateral Lung Nodules
Li AX, Flores K, Canavan ME, Boffa DJ, Blasberg JD. Adjuvant Chemotherapy for T4 Non-Small Cell Lung Cancer with Additional Ipsilateral Lung Nodules. The Annals Of Thoracic Surgery 2021, 113: 421-428. PMID: 33684345, DOI: 10.1016/j.athoracsur.2021.02.042.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerDifferent ipsilateral lobeCell lung cancerAdditional tumor nodulesT4 non-small cell lung cancerAdjuvant chemotherapyIpsilateral lobeT4 diseaseTumor nodulesLung cancerT4 tumorsOverall survivalSurgical resectionIIIA non-small cell lung cancerAdjuvant multiagent chemotherapyResectable stage IINational Cancer DatabaseFurther prospective studiesLymph node metastasisMultiagent chemotherapyNode metastasisPrimary outcomeProspective studyPatient populationCancer DatabaseA Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications.
Colquhoun DA, Leis AM, Shanks AM, Mathis MR, Naik BI, Durieux ME, Kheterpal S, Pace NL, Popescu WM, Schonberger RB, Kozower BD, Walters DM, Blasberg JD, Chang AC, Aziz MF, Harukuni I, Tieu BH, Blank RS. A Lower Tidal Volume Regimen during One-lung Ventilation for Lung Resection Surgery Is Not Associated with Reduced Postoperative Pulmonary Complications. Anesthesiology 2021, 134: 562-576. PMID: 33635945, PMCID: PMC8274370, DOI: 10.1097/aln.0000000000003729.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureOne-lung ventilationPostoperative pulmonary complicationsEnd-expiratory pressurePulmonary complicationsProtective ventilationTidal volumeThoracic surgeryMajor postoperative pulmonary complicationsVentilation regimenLung resection surgeryRetrospective observational analysisThoracic Surgeons databaseMedian tidal volumeLung resection proceduresUnmatched cohortMajor surgeryPrimary outcomeResection surgerySurgeons databaseIndependent associationResection proceduresDecreased oddsIntraoperative dataComplications
2018
Robotic-Assisted Lobectomies in the National Cancer Database
Arnold BN, Thomas DC, Narayan R, Blasberg JD, Detterbeck FC, Boffa DJ, Kim AW. Robotic-Assisted Lobectomies in the National Cancer Database. Journal Of The American College Of Surgeons 2018, 226: 1052-1062.e15. PMID: 29574177, DOI: 10.1016/j.jamcollsurg.2018.03.023.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseRobotic lobectomyLung cancerCancer DatabaseOutcomes of patientsPropensity-matched analysisThoracoscopic surgery lobectomyExperienced hospitalsOverall conversion ratePerioperative morbidityPrimary outcomePatient selectionAttendant sequelaeOpen procedureLobectomyAssisted LobectomyHigh mortalityHospitalPatientsMortalityIndividual hospitalsRate of conversionSignificant differencesYears of experienceOutcomesSpontaneous regionalization of esophageal cancer surgery: an analysis of the National Cancer Database
Arnold BN, Chiu AS, Hoag JR, Kim CH, Salazar MC, Blasberg JD, Boffa DJ. Spontaneous regionalization of esophageal cancer surgery: an analysis of the National Cancer Database. Journal Of Thoracic Disease 2018, 10: 1721-1731. PMID: 29707326, PMCID: PMC5906219, DOI: 10.21037/jtd.2018.02.12.Peer-Reviewed Original ResearchLow-volume hospitalsNational Cancer DatabaseProportion of patientsHigh-volume hospitalsEsophageal cancer surgeryEsophagectomy patientsHigh-risk attributesCancer surgeryEra 2Cancer DatabaseHigh-risk patientsPrimary outcomeEsophageal cancerEra 1Retrospective analysisMortality ratePatientsEsophagectomyHospitalSurgeryFurther studiesCancerCliniciansMortalityProportion
2017
Effectiveness of local therapy for stage I non–small-cell lung cancer in nonagenarians
Arnold BN, Thomas DC, Rosen JE, Salazar MC, Detterbeck FC, Blasberg JD, Boffa DJ, Kim AW. Effectiveness of local therapy for stage I non–small-cell lung cancer in nonagenarians. Surgery 2017, 162: 640-651. PMID: 28697883, DOI: 10.1016/j.surg.2017.04.025.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overCarcinoma, Non-Small-Cell LungConfidence IntervalsDatabases, FactualDisease-Free SurvivalFemaleGeriatric AssessmentHumansKaplan-Meier EstimateLogistic ModelsLung NeoplasmsMaleMultivariate AnalysisNeoplasm InvasivenessNeoplasm StagingOdds RatioPneumonectomyProportional Hazards ModelsRadiotherapyRegistriesRisk AssessmentSecondary PreventionSurvival AnalysisConceptsCell lung cancerLocal therapyLung cancerStage IRelative survivalStereotactic body radiation therapyNational Cancer DatabaseBetter overall survivalBody radiation therapyOlder patientsOverall survivalPatient ageYounger patientsOverall mortalityPrimary outcomeCancer DatabaseTreatment outcomesTreatment decisionsRadiation therapyPatientsTherapyCancerNonagenariansTreatmentSurvivalValidating the Thoracic Revised Cardiac Risk Index Following Lung Resection
Thomas DC, Blasberg JD, Arnold BN, Rosen JE, Salazar MC, Detterbeck FC, Boffa DJ, Kim AW. Validating the Thoracic Revised Cardiac Risk Index Following Lung Resection. The Annals Of Thoracic Surgery 2017, 104: 389-394. PMID: 28499655, DOI: 10.1016/j.athoracsur.2017.02.006.Peer-Reviewed Original ResearchConceptsAdditional cardiac evaluationIschemic heart diseaseLarger multi-institutional datasetsCardiac complicationsLung resectionRenal comorbiditiesCardiac evaluationCerebrovascular diseaseHeart diseaseRisk factorsMulti-institutional datasetSurgeons National Surgical Quality Improvement Program datasetNational Surgical Quality Improvement Program datasetCardiac complication ratesMajor cardiac complicationsPreoperative risk factorsUnderwent pneumonectomyCardiac indexComplication ratePrimary outcomeRisk classesMalignant diseaseOpen procedureAmerican CollegeHigh risk
2016
Lung Cancer in the Very Young: Treatment and Survival in the National Cancer Data Base
Arnold BN, Thomas DC, Rosen JE, Salazar MC, Blasberg JD, Boffa DJ, Detterbeck FC, Kim AW. Lung Cancer in the Very Young: Treatment and Survival in the National Cancer Data Base. Journal Of Thoracic Oncology 2016, 11: 1121-1131. PMID: 27103511, DOI: 10.1016/j.jtho.2016.03.023.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerNational Cancer Data BaseYounger patientsOlder patientsLung cancerRelative survivalStage IAdvanced stage non-small cell lung cancerCell lung cancerYears of ageAggressive therapyAggressive treatmentOverall survivalPatient demographicsPrimary outcomeTreatment patternsTumor characteristicsNSCLC casesPatientsStage IIIDetailed stagingSurvival informationOlder groupDistinct subsetsCancerAdjuvant Chemotherapy for T3 Non–Small Cell Lung Cancer with Additional Tumor Nodules in the Same Lobe
Salazar MC, Rosen JE, Arnold BN, Thomas DC, Kim AW, Detterbeck FC, Blasberg JD, Boffa DJ. Adjuvant Chemotherapy for T3 Non–Small Cell Lung Cancer with Additional Tumor Nodules in the Same Lobe. Journal Of Thoracic Oncology 2016, 11: 1090-1100. PMID: 27013407, DOI: 10.1016/j.jtho.2016.03.009.Peer-Reviewed Original ResearchConceptsAdditional tumor nodulesAdjuvant chemotherapyT3 tumorsSame lobeTumor nodulesPostoperative chemotherapyOverall survivalSurgical resectionSurvival advantageNon-small cell lung cancerNational Cancer Data BaseNon-small cell lungAdditional pulmonary nodulesAdjuvant chemotherapy subgroupSurvival of patientsCell lung cancerSeparate tumor nodulesChemotherapy subgroupPrimary outcomeCell lungLung cancerChemotherapyCox modelRelative survivalPatients
2015
The Surgical Apgar Score in esophagectomy
Janowak CF, Blasberg JD, Taylor L, Maloney JD, Macke RA. The Surgical Apgar Score in esophagectomy. Journal Of Thoracic And Cardiovascular Surgery 2015, 150: 806-812. PMID: 26234458, DOI: 10.1016/j.jtcvs.2015.07.017.Peer-Reviewed Original ResearchConceptsSurgical Apgar ScoreMajor morbidityApgar scorePostoperative complicationsMultivariate analysisPreoperative patient characteristicsShort-term outcomesBody mass indexStrongest predictorElective esophagectomyTranshiatal techniqueSurgical populationIntraoperative detailsIntraoperative variablesPatient characteristicsDiabetes mellitusPrimary outcomeRetrospective reviewMass indexProspective studyCare modificationsMalignant diseaseRisk factorsUnivariate analysisImproved outcomes