Featured Publications
From taboo to treatment: The emergence of psychedelics in the management of pain and opioid use disorder
Weleff J, Nunes J, Costa G, Sofuoglu M, MacLean R, De Aquino J. From taboo to treatment: The emergence of psychedelics in the management of pain and opioid use disorder. British Journal Of Clinical Pharmacology 2024, 90: 3036-3053. PMID: 38627909, PMCID: PMC11480258, DOI: 10.1111/bcp.16045.Peer-Reviewed Original ResearchOpioid use disorderChronic painLong-term opioid therapyManagement of chronic painPain management alternativeOpioid-induced analgesiaInnovative treatment optionsManagement of painReverse painCentral sensitizationOpioid therapyPain controlTreatment optionsClinical challengeClinical trialsPainPotential therapeutic applicationsPain experiencePotential of psychedelicsNovel therapeuticsHuman evidenceOpioid crisisNeurobiological substratesOpioidExploration of novel therapeutics
2023
Design and development of a digital shared decision-making tool for stroke prevention in atrial fibrillation
Nunes J, Baykaner T, Pundi K, DeSutter K, Hills M, Mahaffey K, Sears S, Morin D, Lin B, Wang P, Stafford R. Design and development of a digital shared decision-making tool for stroke prevention in atrial fibrillation. JAMIA Open 2023, 6: ooad003. PMID: 36751465, PMCID: PMC9893868, DOI: 10.1093/jamiaopen/ooad003.Peer-Reviewed Original ResearchAtrial fibrillationStroke preventionSDM toolsAmerican Heart AssociationCommon cardiac arrhythmiaMultisite clinical trialAppropriate anticoagulationIschemic strokeAF patientsHeart AssociationTreatment acceptanceClinical trialsContent identificationTreatment outcomesClinician experienceHealth literacyCardiac arrhythmiasClinicians toolsPatientsPatient feedbackPatient advocatesDecision regretUser engagementPatient toolsInformation delivery
2022
The ENHANCE-AF clinical trial to evaluate an atrial fibrillation shared decision-making pathway: Rationale and study design
Baykaner T, Pundi K, Lin B, Lu Y, DeSutter K, Lhamo K, Garay G, Nunes JC, Morin DP, Sears SF, Chung MK, Paasche-Orlow MK, Sanders LM, Bunch TJ, Hills MT, Mahaffey KW, Stafford RS, Wang PJ. The ENHANCE-AF clinical trial to evaluate an atrial fibrillation shared decision-making pathway: Rationale and study design. American Heart Journal 2022, 247: 68-75. PMID: 35092723, DOI: 10.1016/j.ahj.2022.01.013.Peer-Reviewed Original ResearchConceptsAtrial fibrillationClinical trialsTransient ischemic attackDecisional Conflict ScaleWishes of patientsDecision aidAF careAnticoagulation adherenceAnticoagulation useIndex visitIschemic attackMajor bleedingAnticoagulation therapyUsual careSecondary outcomesPrimary outcomePatient satisfactionStroke reductionClinician satisfactionHealth literacyClinicians toolsTreatment planNew decision aidDecision-making experiencesPatients